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7 recruiting studies matching your filters

Biofluid Research on Age-Related or Inherited Neurodegeneration (BRAIN)

The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history informat…

Frontotemporal Degeneration (FTD)ALS (Amyotrophic Lateral Sclerosis)Primary Progressive Aphasia (PPA)+12 more

Estimated

~$10 – $750

University of PennsylvaniaNCT07798700

Phase 1

A Phase 1/2 Open-Label, Ascending Dose, Multicenter Study to Evaluate the Safety and Preliminary Efficacy of AVB-101 Administered by Bilateral Intrathalamic Infusion in Subjects With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

The goal of this clinical study is to learn about an investigational gene therapy product called AVB-101, which is designed to treat a disease called Frontotem…

Frontotemporal DementiaFTDFTD-GRN+1 more

Estimated

~$10 – $8,750

AviadoBio LtdNCT06064890

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents the formalized integration of ARTFL (U54 NS092089; funded through 2019) and LE…

Frontotemporal Lobar Degeneration (FTLD)Progressive Supranuclear Palsy (PSP)Corticobasal Degeneration (CBD)+11 more

Estimated

~$10 – $750

Mayo ClinicNCT04363684

University of Pennsylvania Centralized Observational Research Repository on Neurodegenerative Disease (UNICORN)

The aim of this study is to create a repository of both cross-sectional and longitudinal data, including cognitive, linguistic, imaging and biofluid biological…

Frontotemporal Degeneration(FTD)Primary Progressive Aphasia(PPA)Familial Frontotemporal Lobar Degeneration (fFTLD)+6 more

Estimated

~$10 – $750

University of PennsylvaniaNCT04715399

ALS Translational Research Program

The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings…

Amyotrophic Lateral SclerosisALS (Amyotrophic Lateral Sclerosis)ALS With Frontotemporal Dementia (ALS/FTD)+2 more

Estimated

~$10 – $1,125

ALS Therapy Development InstituteNCT06885918

Phase 2

Functional Neuroimaging to Examine Affective Symptoms and Cognition in Frontotemporal Dementia

The goal of this clinical trial is to learn if vortioxetine improves mood symptoms and cognition in patients with early-stage behavioral variant Frontotemporal…

Fronto-temporal DementiaFronto-temporal Lobar DementiaFrontotemporal Degeneration+3 more

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT06604520

A Wearable Sensor Platform for Remote Monitoring of Individuals on the Frontotemporal Dementia Spectrum

The primary objective of this clinical study is to provide the initial validation for monitoring biomarkers of symptoms and functioning for individuals with fr…

Frontotemporal Lobar Degeneration (FTLD)Frontotemporal Dementia (FTD)Corticobasal Degeneration+1 more

Estimated

~$10 – $1,125

BioSensicsNCT07569367