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Observational
A Pilot Randomized Clinical Trial of Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Steroid Resistant Nephrotic Syndrome in Children
Children with steroid resistant nephrotic syndrome (SRNS) are exposed to prolonged courses of immunosuppressant medications. Given the adverse side effect prof…
Nephrotic Syndrome in ChildrenMinimal Change DiseaseFocal Segmental Glomerulosclerosis
Northwell HealthNCT05583942
Phase 1
AMPK-activation by Metformin in FSGS: AMP-FSGS
The primary objective of this study is to determine whether extended-release MF (in addition to standard of care (S-o-C)) is superior to placebo in reducing po…
Focal Segmental Glomerulosclerosis
Yale UniversityNCT06090227
Phase 2
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Praliciguat in Patients With Biopsy-Confirmed Focal Segmental Glomerulosclerosis
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study designed to evaluate the efficacy and safety of praliciguat in adults with b…
Focal Segmental Glomerulosclerosis
Akebia TherapeuticsNCT07268638