The purpose of this study is to test whether the combination of the drugs called tacrolimus (Tac), methotrexate (MTX) and new dosing strategy of another drug c…

GVHD,AcuteAcute LeukemiaMyelodysplastic Syndromes+1 more

~Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06315309

CXC-chemokine Ligand 9 (CXCL9) and Endothelial Activation and Stress Index (EASIX) for Prediction of Acute Graft Versus Host Disease

The prediction of severe acute GVHD before it occurs is of high importance for ensuing clinical decisions and overall success of allogeneic SCT. The key immuno…

GVHD,Acute

~Estimated

~$10 – $750

Henry Ford Health SystemNCT05718791

Phase 1

Phase I, First in Human, Open Label Study to Evaluate Safety and Tolerability of TRX103 Cells in Subjects With Hematological Malignancies Undergoing HLA-mismatched Related or Unrelated Hematopoietic Stem Cell Transplantation (HSCT)

The purpose of this Phase 1, first in human open-label study is to assess the safety and tolerability of TRX-103 in patients with hematological malignancies un…

Hematologic MalignancyGvHDGVHD,Acute+8 more

~Estimated

~$10 – $8,750

Tr1X, Inc.NCT06462365