Browse Studies — Arctuva

Phase 2

A Phase II Trial of Trifluridine/Tipiracil Plus Oxaliplatin in Patients With Advanced or Metastatic Biliary Tract Cancer Following First-Line Therapy

Participants are eligible for this study who were treated for advanced biliary tract cancer (BTC) but the treatment either did not make the cancer better or is…

Biliary Tract CancerBiliary Tract NeoplasmsCholangiocarcinoma+2 more

Estimated

~$10 – $6,250

Case Comprehensive Cancer CenterNCT07146646

Phase 2

A Phase IIa Clinical Trial of First-Line Cyclical Gemcitabine, Cisplatin, and Durvalumab Alternating With Pemigatinib for Advanced Biliary Tract Cancers With FGFR2 Alterations

This phase II trial tests how well giving gemcitabine, cisplatin and durvalumab alternating with pemigatinib for the treatment of biliary tract cancer with FGF…

Locally Advanced Ampulla of Vater CarcinomaLocally Advanced Biliary Tract CarcinomaLocally Advanced Extrahepatic Cholangiocarcinoma+20 more

Estimated

Phase 2

A Multi-Institutional Phase 2 Evaluation of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer

The purpose of this study is to evaluate the anti-tumor efficacy of daraxonrasib monotherapy in patients with unresectable or advanced/metastatic, KRAS-mutant …

Biliary Tract CancersIntrahepatic Cholangiocarcinoma (Icc)Extrahepatic Cholangiocarcinoma+3 more

Estimated

~$10 – $6,250

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT07793253

Phase 1

Safety of Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Biliary Tract Cancer Patients With Peritoneal Metastases

This phase I trial studies the side effects of pressurized intraperitoneal aerosolized chemotherapy (PIPAC) nab-paclitaxel in combination with gemcitabine and …

Distal Bile Duct AdenocarcinomaGallbladder CarcinomaIntrahepatic Cholangiocarcinoma+5 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT05285358