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8 recruiting studies matching your filters

NADIR Trial: A Principal Investigator-Initiated, Single-Center, Open-Label, Active-Controlled Phase 2a Study of High-Dose Nicotinamide (Vitamin B3) Supplementation in Adults With Mild to Moderate Primary Open-Angle Glaucoma (POAG)

The goal of this clinical trial is to learn whether a high-dose vitamin B3 supplement called nicotinamide can protect retinal nerve cells in adults with primar…

Glaucoma, Open-anglePrimary Open Angle Glaucoma (POAG)

Estimated

~$10 – $6,250

University of ChicagoNCT07808333

Phase 4

Multicenter, Randomized, Double-masked Trial to Evaluate the Safety and Efficacy of iDose® TR (Travoprost Intraocular Implant) in Conjunction With the Placement of iStent Infinite in Subjects With Open-angle Glaucoma or Ocular Hypertension

Adult subjects with elevated intraocular pressure will be randomized to receive iStent infinite trabecular bypass system plus a travoprost intraocular implant …

Glaucoma, Open-Angle

Estimated

~$10 – $8,750

Glaukos CorporationNCT06066645

Observational

An Open-Label Study to Evaluate the Safety and Efficacy of Repetitive, Transorbital Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies

The overall aim of this study is to see whether long-term electrical stimulation with a home-stimulation device works well and is safe for the treatment of ope…

GlaucomaGlaucoma, Open-AngleOptic Nerve Diseases

Estimated

~$10 – $6,250

Stanford UniversityNCT05626426

Observational

Visual Outcomes and Patient Satisfaction in Subjects With Stable Open-angle Glaucoma Undergoing Concurrent Minimally Invasive Glaucoma Surgery and IOL Implantation With an Extended-depth-of-focus IOL

This study is designed to determine how well patients with glaucoma can see following cataract surgery with a special type of lens called an extended-depth-of-…

Glaucoma, Open-AngleCataract

Estimated

~$10 – $7,500

Vold Vision P.L.L.CNCT05624398

Observational

Randomized Trial of Hydrus Microstent Versus Goniotomy

The goal of this clinical trial is to evaluate the comparative efficacy and safety of Hydrus Microstent, incisional goniotomy, and excisional goniotomy when co…

GlaucomaGlaucoma, Open-Angle

Estimated

~$10 – $7,500

Massachusetts Eye and Ear InfirmaryNCT06289491

Phase 4

The Effect of Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients Using Brimonidine 0.2%, 0.15%, or 0.1%

Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at loweri…

GlaucomaGlaucoma, Open-AngleGlaucoma; Drugs+3 more

Estimated

~$10 – $6,250

Tulane UniversityNCT04007276

Phase 4

Multicenter, Randomized, Double-masked, Parallel Group Trial to Evaluate the Safety and Efficacy of iDose® TR (Travoprost Intracameral Implant) in Conjunction With Cataract Surgery vs. Cataract Surgery Alone

This trial will evaluate the safety and IOP -lowering efficacy of administering an iDose TR (travoprost intracameral implant) in conjunction with cataract surg…

Glaucoma, Open-angleOcular Hypertension (OHT)Phacoemulsification Cataract Surgery

Estimated

~$10 – $8,750

Glaukos CorporationNCT06848946

Phase 3

A Randomized, Double-blind, Multiple Dose, Parallel-group, Two-arm, Multicenter, Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® (Bimatoprost Ophthalmic Solution) 0.01% in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioeq…

Glaucoma, Open-AngleOcular Hypertension

Estimated

~$10 – $8,750

Amneal Pharmaceuticals, LLCNCT05401357