This is a single-center, open-label, dose-escalating Phase 0 trial that will enroll participants with a confirmed diagnosed recurrent high-grade glioma (grade …

High Grade GliomaGliomaGlioma, Malignant+1 more

~Estimated

~$10 – $7,500

Nader SanaiNCT05773326

Phase 1

Early Phase 1 Window of Opportunity Study of Oral DSP-0390 in Gliomas

This study focuses on determining the pharmacokinetic and pharmacodynamic effect of DSP-0390 in brain and blood from patients with IDH-mutant glioma undergoing…

Glioma, MalignantIDH Mutation

~Estimated

~$10 – $6,250

Washington University School of MedicineNCT06636162

Phase 1

A Phase I Study of Repeated Neural Stem Cell-Based Virotherapy and Standard Radiation and Chemotherapy for Newly Diagnosed High-Grade Glioma

The goal of this clinical trial is to learn about the safety and feasibility of administering repeated doses of neural stem cell (NSC)-conditionally replicativ…

Glioma, MalignantNew Diagnosis Tumor

~Estimated

~$10 – $6,250

Northwestern UniversityNCT06169280

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