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Phase 1
The Role of Bimatoprost in Graves' Periorbitopathy
Testing whether Bimatoprost, a topical eye drop used for glaucoma, can be used to induce periorbital fat atrophy in patients with Graves' disease
Graves Ophthalmopathy
Johns Hopkins UniversityNCT03708627
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam l…
Thyroid Eye DiseaseGraves OphthalmopathyGraves Disease
Walter Reed National Military Medical CenterNCT06275373
Phase 2
A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled i…
Thyroid Eye DiseaseGraves OrbitopathyEndocrine System Diseases+9 more
Sling Therapeutics, Inc.NCT06112340