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Phase 1
A Feasibility Study of E7 TCR-T Cell Induction Therapy for Locoregionally Advanced HPV-Associated Cancers
The goal of this study is to determine the feasibility of administration of a single dose of E7 TCR-T cells as induction therapy prior to definitive treatment …
HPV-Associated Cervical CarcinomaHPV-Related CarcinomaHPV-Related Malignancy+14 more
Christian HinrichsNCT05639972
Phase 2
A Phase II Trial of T Cell Receptor Gene Therapy Targeting Human Papillomavirus ( HPV) 16 E7 for HPV-Associated Cancers
This is a phase II clinical trial to assess the clinical activity of immunotherapy with E7 TCR-T cells for metastatic HPV-associated cancers. HPV-associated ca…
Cervical CancerThroat CancerOropharynx Cancer+18 more
Christian HinrichsNCT05686226