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10 recruiting studies matching your filters

A Phase II Randomized Trial of Enteral Nutrition Versus Standard of Care in Allogeneic Hematopoietic Stem Cell Transplantation

This is a randomized controlled phase II trial which will enroll 112 patients with a diagnosis of a blood cancer or a serious blood disorder who plan to underg…

Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT)

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of NebraskaNCT07315165

Phase 1

Technical Development of Xe MRI in Children and Adults

The goal of this study is to develop and optimize new proton (1H; conventional MRI) and Xe gas MRI techniques to assess regional cardiopulmonary structure and …

HSCTLung Transplant Recipient

Estimated

~$500 – $6,750

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT07823010

Phase 1

Pilot Study of Scaling Busulfan Dose to Body Surface Area in Children Undergoing Hematopoietic Stem Cell Transplantation

The goal of this pilot study is to determine if scaling the first busulfan dose to Body Surface Area (BSA) in children with a BSA ≥0.5 m2 and using a BSA-bande…

Busulfan Pharmacokinetic AnalysisBusulfan DosingHematopoietic Stem Cell Transplant (HSCT)+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Children's Hospital of PhiladelphiaNCT07792369

Phase 1

Assessing Pulmonary Changes in Hematopoietic Stem-Cell Transplantation Patients and Patients With Rare-Lung Diseases Using Hyperpolarized Xe MR Lung Imaging

This will be an un-blinded, open-label study of children and adults, including those who are being evaluated for or who have undergone HSCT, those with existin…

HSCTRespiratoryGas Exchange Impairment

Estimated

~$500 – $6,750

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT07823036

Observational

Massage Impact on Sleep in Hospitalization for Pediatric Oncology and Stem Cell Transplant Patients

This study aims to determine the impact of massage therapy for pediatric patients receiving intensive chemotherapy or stem cell transplant (SCT).

CancerPediatric CancerChemotherapy Effect+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Children's Hospital of PhiladelphiaNCT06892158

A Prospective Approach for the Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation

Background: Stem cell transplants (called hematopoietic stem cell transplantation, or HSCT) are used to treat various diseases. But when the cells for this pr…

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT06093867

Phase 2

Efficacy and Safety of PUL-042 Inhalation Solution in Reducing Lower Respiratory Tract Complications in Patients With Hematologic Malignancies and Recipients of Hematopoietic Stem Cell Transplantation (HSCT) With Documented Viral Infections With PIV, hMPV or RSV

The purpose of this research study is to try to see whether an experimental drug, PUL 042 Inhalation Solution (PUL 042), is effective in reducing the severity …

Hematologic MalignanciesHematopoietic Stem Cell Transplant (HSCT)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Pulmotect, Inc.NCT06665100

Phase 2

A Randomized, Placebo-Controlled Phase 2 Study of IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

This is a Phase 2 study of the study drug, ivosidenib (a mutant IDH1 inhibitor), compared to placebo, given to patients with IDH1-mutant acute myeloid leukemia…

IDH1 MutationAcute Myeloid Leukemia (AML)Hematopoietic Stem Cell Transplant (HSCT)

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT06707493

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy and pulmonary morbidity affects as many as 25% of children receiving transplant. Ea…

Hematopoietic Stem Cell Transplant (HSCT)Diffuse Alveolar HemorrhageThrombotic Microangiopathies+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT04098445

Phase 1

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

This is a Phase I dose-escalation study to evaluate the safety of norovirus -specific T-cell (NST) therapy for chronic norovirus infection in participants foll…

Viral InfectionHematopoietic Stem Cell Transplantation (HSCT)Primary Immunodeficiency Disorders (PID)

Estimated

~$150 – $2,700

Actual pay is set by the research site.

Children's National Research InstituteNCT04691622