The goal of this clinical trial is to assess the safety and tolerability of a virus replicon particle (VRP) encapsulated saRNA encoding IL-12 when injected int…

Head and Neck Cancers- Squamous CellHead and Neck CancerSolid Tumors+10 more

~Estimated

~$10 – $8,750

VLP TherapeuticsNCT06736379

Phase 1

Phase 1b/2a Study of RiMO-301 and Hypofractionated Radiotherapy With A PD-1 Inhibitor for the Treatment of Unresectable, Recurrent or Metastatic Head-Neck Cancer

This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with hypofractionated radiation and a PD-1 Inhibitor in patients with unresecta…

Head Neck CancerIntratumoral Injection

~Estimated

~$10 – $8,750

Coordination Pharmaceuticals, Inc.NCT05838729

Observational

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy for Pain Palliation in Head, Neck, & Brachial Cancer

This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, …

Head Neck CancerSquamous Cell Cancer of Head and Neck (SCCHN)Cancer Pain

~Estimated

~$10 – $6,250

University of VirginiaNCT07405645