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66 recruiting studies matching your filters

A Phase I, Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD3974 After Single and Multiple Ascending Dosing to Healthy Participants

The purpose of this study is to assess the safety and tolerability of AZD3974 and characterize the pharmacokinetics (PK) of AZD3974 following oral administrati…

Healthy Participants

Estimated

~$10 – $7,500

AstraZenecaNCT07290283

Phase 1

A Sequential, Phase 1a/1b, Double-blind, 2-part Study to Investigate the Safety, Tolerability, Microbiological Response, and Pharmacokinetics of Rev-56 for Inhalation Compared With Placebo in Healthy Adult Participants and Adult Non-cystic Fibrosis Bronchiectasis (NCFB) Patients With Chronic Pseudomonas Aeruginosa

This is a Phase 1a/1b study to test the safety, tolerability, microbiological response, and pharmacokinetics of inhaled Rev-56 compared to placebo in adult hea…

Healthy ParticipantsNon-cystic Fibrosis Bronchiectasis

Estimated

~$10 – $8,750

Revagenix, Inc.NCT07709494

Phase 1

A PHASE 1, FIRST IN HUMAN, RANDOMIZED, DOUBLE-BLIND, SPONSOROPEN, PLACEBO-CONTROLLED, SINGLE- AND MULTIPLE DOSE ESCALATION, PARALLEL GROUP STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF PF-07832837 IN HEALTHY PARTICIPANTS AND PARTICIPANTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics of escalating single and repeat doses of PF-07832837 in healthy particip…

Healthy ParticipantsAtopic Dermatitis

Brain Mechanisms Underlying Neurotypical and Disordered Speech

This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several system…

Stuttering, DevelopmentalDyslexiaHealthy Participants

Estimated

~$10 – $6,250

Boston University Charles River CampusNCT07459803

Observational

Translating Behavioral Economics Strategies to Culturally Tailor a Mobile Health Mindfulness Intervention to Reduce Risky Drinking Behaviors in Emerging Adult College Student Students

The goal of this clinical trial is to examine the feasibility and acceptability of different types of text messages and a integrated gaming app to increase eng…

Healthy ParticipantsFeasibility StudiesAcceptability

Estimated

~$10 – $6,250

Florida State UniversityNCT07170202

Phase 1

Neural Effects of Continuous Intravenous Infusion of N,N-dimethyltryptamine (DMT)

This study examines how the psychedelic substance DMT affects the human brain when administered by the intravenous (IV) route. DMT is a naturally occurring che…

Healthy Participants Study

A Phase 1, Single Dose, Open-Label, Parallel Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of INCA033989 Following Subcutaneous or Intravenous Administration in Healthy Adult Participants

This study is being conducted to evaluate the pharmacokinetics, safety, and tolerability of INCA033989 following subcutaneous (SC) or intravenous administratio…

Healthy Participants

Estimated

~$10 – $8,750

Incyte CorporationNCT07448155

Phase 1

A Phase 1 Single and Multiple Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Healthy Participants (Part A) and the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SR604 in Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency (Part B)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) of SR604 in healthy participants (Part A) an…

Healthy ParticipantsHemophilia AHemophilia B+1 more

Estimated

~$10 – $8,750

Equilibra Bioscience LLCNCT06349473

Phase 1

A Phase 1, Open-label, Randomized, 2-Treatment, 2-Period, Crossover Study to Assess the Bioequivalence of Navlimetostat Wet-Granulation Tablet Versus the Dry-Granulation Tablet Formulation in Healthy Adult Female (as Assigned at Birth) Participants Who Are Individuals Not of Childbearing Potential

This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy ad…

Healthy Participants

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07544628

Phase 1

A Phase 1, Open-Label, Randomized, Single-Dose, Three-Treatment, Three-Period, Six-Sequence Crossover Pharmacokinetic Study to Evaluate the Bioequivalence of Two Casdatifan (AB521) Tablet Strengths and Food Effect in Healthy Adult Participants

The purpose of this study is to compare the single-dose pharmacokinetics (PK) of casdatifan 100 mg versus four 25 mg tablets under fasting conditions in health…

Healthy Participants

Estimated

~$10 – $8,750

Arcus Biosciences, Inc.NCT07641881

Observational

Effects of Fresh Mango as a Table Sugar Replacement on Postprandial Intestinal Permeability and Inflammation Following a High-Sugar Breakfast.

Systemic inflammation and intestinal hyperpermeability (disruption of the gut barrier which allows nutrient molecules and bacteria to enter the bloodstream) ar…

Healthy Participants

Estimated

~$10 – $6,250

Ball State UniversityNCT07650058

Observational

Cognition and Ultrasound

Our primary goal is to investigate the role of Low-Intensity Focused Ultrasound (LIFU) neuromodulation on deep brain targets, and its potential to improve cogn…

Healthy Participants

Estimated

~$10 – $6,250

University of MinnesotaNCT07220655