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185 recruiting studies matching your filters

A Phase 1, Randomized, Blinded, Placebo-Controlled, Single- and Multiple-Ascending-Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB145 in Healthy Adult Participants

In this study, researchers will learn for the first time about the safety of a study drug called BIIB145 and how the body responds to it. This is a "Phase 1" s…

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translation…

Healthy VolunteerProstate CancerHead and Neck Cancer+10 more

Estimated

~$10 – $750

Washington University School of MedicineNCT04354064

Phase 4

A Phase IV, Open-label, Single-group Study Evaluating KarXT Concentrations in the Breast Milk and Plasma of Healthy Lactating Female Participants

The purpose of this study is to characterize the PK of xanomeline and trospium in breast milk and plasma in healthy lactating female participants, following mu…

Healthy Volunteers

Estimated

~$10 – $8,750

Karuna Therapeutics, Inc., a Bristol Myers Squibb companyNCT07257120

Phase 2

Evaluation of Ultralow Dose PET Imaging for Detecting 18F-FDG Uptake

The goal of this clinical trial is to evaluate an investigational ultralow dose PET imaging technique for cancer detection and monitoring. The main question it…

Healthy VolunteerCancer

Estimated

~$10 – $7,500

Akiva MintzNCT06956391

Observational

Kaempferol Absorption and Pharmacokinetics Evaluation (K.A.P.E.)

This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plan…

No DiseaseMitochondria HealthLongevity+2 more

Estimated

~$10 – $6,250

University of PittsburghNCT07322406

Phase 1

Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy Volunteers

Background: Researchers want see if three new HIV (human immunodeficiency virus) vaccines are safe. Two vaccines are carried by live adenoviruses, which are n…

Healthy Volunteer

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT03878121

Phase 1

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Doses of MT-701 in Healthy Participants

First-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple doses of MT-701 in healthy particip…

Healthy Volunteers

Estimated

~$10 – $8,750

Mirador Therapeutics, Inc.NCT07396909

Toward Precision Radiotherapy: Physiological Modeling of Respiratory Motion Based on Ultra-quality 4D-MRI

The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic res…

Healthy VolunteersLiver CancerLung Cancer

Estimated

~$10 – $750

University of VirginiaNCT04657042

Phase 1

A Phase 1, Double-blinded, Placebo-controlled Study of Single Ascending Doses of NNC4004-0002 in Adults With Asymptomatic Hyperuricemia

This study will evaluate an investigational drug called NNC4004-0002. "Investigational" means NNC4004-0002 has not been approved for sale/ for clinical use or …

Healthy VolunteersHyperuricemia

Estimated

~$10 – $7,500

Novo Nordisk A/SNCT06859073

Ability of Emergency Medicine Doctors to Use Ultrasound to View Muscle Layers of the Abdominal Wall

The American College of Emergency Physicians (ACEP) views ultrasound-guided nerve blocks to be a core skill for emergency medicine physicians. They are used wi…

Healthy Volunteers

Estimated

~$10 – $1,125

Corewell Health SouthNCT06955013

Observational

Temporal Interference Methods for Non-invasive Deep Brain Stimulation

In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal…

Healthy Volunteers

Estimated

~$10 – $6,250

Indiana UniversityNCT07215299

Phase 4

Evaluation of Energy Drinks on Electrocardiographic Parameters: A Randomized, Double Blind, Controlled, Crossover, Proof-of-concept Study

This is a clinical trial looking at the impact of energy drinks on heart related parameters. The study will enroll 3 participants who will be exposed to 8 diff…

Healthy VolunteersSafety After Oral Intake

Estimated

~$10 – $6,250

University of the PacificNCT07212803