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121 recruiting studies matching your filters

A Double Blind, Randomized Trial Investigating the Safety, Feasibility, and Mechanisms of Psychedelics in Healthy Older Adults With Low Well-being as Moderated by Biomarkers for Preclinical Alzheimer's Disease

This study is being conducted to understand changes in brain activity following administration of two different drugs (Psilocybin and Dextromethorphan) in olde…

Anhedonia in Healthy VolunteersOlder Adults (50-90 Years)

Estimated

~$10 – $7,500

Jennifer MitchellNCT07386730

Phase 2

The Neurobiology of Suicide

Background: There are no good treatments for people considering suicide. Researchers want to study suicide with questions, blood tests, brain imaging, and sle…

Healthy VolunteersDepression

Estimated

~$10 – $5,625

National Institute of Mental Health (NIMH)NCT02543983

Phase 1

A Phase 1 Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Escalating Dose Trial in Healthy Participants to Assess Pharmacokinetics, Safety, and Tolerability of TEV-56286 at Clinical and Supratherapeutic Doses

The purpose of the trial is to evaluate the pharmacokinetics, safety, and tolerability of TEV-56286 at different doses. The main objective is to describe how …

Healthy Volunteers

Estimated

~$10 – $8,750

Teva Branded Pharmaceutical Products R&D LLCNCT07674940

Observational

A Randomized, Open-label, Evaluator-Blinded, Cross-over Clinical Study to Confirm the Safety and Tolerability of an Ultra Absorbency Menstrual Tampon Compared to a Commercially Marketed Tampon

A Randomized, Open-Label, Evaluator-Blinded, Cross-Over Clinical Study to Confirm the Safety and Tolerability of an Ultra Absorbency Menstrual Tampon Compared …

Safety and Tolerability in Healthy Volunteers

Estimated

~$10 – $8,750

Lyv Life Inc. (dba: Cora)NCT07807891

Controls and Healthy Vasculature Initiative

Background: Diseases involving blood, blood vessels, and immune systems are leading causes of death in the United States. Researchers studying these diseases …

Vascular And Immunologic DiseasesHealthy Volunteers

Documented

$50/visit

National Heart, Lung, and Blood Institute (NHLBI)NCT05403151

Observational

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

Background: Diet-induced thermogenesis (DIT) is the amount of energy one's body uses to eat food, absorb the nutrients from the food, and process those nutrie…

ObesityNormal PhysiologyHealthy Volunteers

Estimated

~$10 – $5,625

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05545306

Care of the Urothelial Cancer Patient and Prospective Collection of Biospecimens From Healthy Volunteers and Urothelial Cancer Patients

Background: Urothelial cancer is cancer of the bladder, ureter, and urethra. Researchers want to better understand what changes in a person s cells and genes …

Bladder CancerUrinary Tract CancerUrothelial Cancer+1 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT02379429

Phase 1

A Phase 1, Placebo-Controlled, Single- and Multiple-Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4178256 in Healthy Participants

The main purpose of this study is to evaluate how well LY4178256 is tolerated and what side effects may occur in healthy participants. Blood tests will be perf…

Healthy Volunteers

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07698210

Phase 1

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

This first-in-human study will establish the human safety and radiation dosimetry of the system A amino acid transport substrate, (R)-3-\[F-18\]fluoro-2-methyl…

Healthy VolunteersRecurrent GliomaBrain Metastases From Extra-cranial Solid Tumors

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT05676489

Observational

Pilot Study of Fermented Papaya Preparation (FPP) Impact on Transepidermal Water Loss of Skin on Face, Arms, and Hands

This pilot study will test how Fermented Papaya Preparation (FPP) impacts overall TEWL of areas that commonly display diminished barrier function, such as the …

Skin Barrier DysfunctionHealthy Volunteers

Estimated

~$10 – $6,250

University of PittsburghNCT07725835

Phase 1

A Phase 1/2a, First-in-human, Randomized, Double-blinded, Placebo-controlled, Dose-finding Study in Healthy Volunteers and Participants With Sickle Cell Disease to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics, pH and Food Effect, and Preliminary Efficacy of BMS-986470

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BM…

Anemia, Sickle CellHealthy Volunteers

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT06481306

Phase 1

A Phase 1, Open-label, 3-Part Study to Assess Potential Drug-Drug Interactions of E2086 When Coadministered Orally With Itraconazole, Carbamazepine, Midazolam, Dextromethorphan, Bupropion, or Combined Oral Contraceptives in Healthy Subjects

The primary purpose of this study is to assess potential drug-drug interactions of E2086 when coadministered orally with Itraconazole, Carbamazepine, Midazolam…

Healthy Volunteers

Estimated

~$10 – $8,750

Eisai Inc.NCT07766369