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121 recruiting studies matching your filters

A Phase 1, Open-label, Single-site, Multi-part, Non-randomized, Parallel-group Study to Assess the Relative Bioavailability of BMS-986435 Tablet Formulations (Parts 1 & 2) and Food Effect on the Selected BMS-986435 Tablet Formulations (Part 3) in Healthy Adult Participants

This study is designed to evaluate the relative bioavailability (rBA) of multiple test tablet formulations of BMS-986435 compared to an equal dose of the BMS-9…

Healthy Volunteers

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07226817

Adaptive Optics Retinal Imaging

Background: \- By the time diseases of the retina are detected, serious damage has often already been done. Researchers want to find better ways of viewing th…

Eye DiseasesHealthy Volunteers

Estimated

~$10 – $675

National Eye Institute (NEI)NCT02317328

Observational

The Effect of Osteopathic Manipulative Techniques on Human Tear Composition

This is a pilot study to determine if osteopathic manipulation can alter the concentration of proteins and lipids in human tears.

No Disease or Condition is Being Directly StudiedThe Focus of the Study in Healthy Volunteers

Estimated

~$10 – $6,250

Lake Erie College of Osteopathic MedicineNCT07633496

Phase 1

An Open-label, Positron Emission Tomography Study to Evaluate Brain Receptor Occupancy, Safety, Tolerability, and Pharmacokinetics After a Single Sublingual Administration of ITI-1284 in Healthy Subjects

The study will be conducted as an open-label and single-center study to evaluate the occupancy of ITI-1284 to the dopamine D2 receptor, serotonin 2A (5-HT2A) r…

Healthy Volunteers

Estimated

~$10 – $8,750

Intra-Cellular Therapies, Inc.NCT06299410

Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Lung Cancer

The purpose of this research study is to test a new process for diagnosing lung cancer by examining changes to your DNA that can be detected from a blood test.…

Lung CancerLung Cancer ScreeningHealthy Volunteers (HV)+1 more

Estimated

~$10 – $750

University of Maryland, BaltimoreNCT07008664

Phase 1

A Phase 1, Randomized, Double-blind, Placebo-controlled, First-in-Human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986533 in Healthy Participants, an Open-label Assessment of Food and pH Effects on the Relative Bioavailability of BMS-986533, and an Open-label Study to Evaluate P-gp- and BCRP-mediated Drug-Drug Interaction Potential of BMS-986533 in Healthy Participants

The purpose of this study is to evaluate the safety and pharmacokinetics of BMS-986533 in healthy participants receiving single and multiple doses, to assess f…

Healthy Volunteers

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07629999

Phase 1

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of LTP001 in Healthy Adult Participants (Part A) and to Evaluate the Efficacy and Safety of LTP001 for the Treatment of Participants With Pulmonary Arterial Hypertension (Part B)

A study to learn about the treatment LTP001 in healthy participants (Part A) and in participants with PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT06649110

Phase 1

A Phase 1, Open-label, Trial of the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-3379 Following a Single Oral Dose in Healthy Male Participants

This is a Phase 1, open label study in healthy male participants to study the Absorption, Distribution, Metabolism, and Excretion of \[14C\]-MRM-3379 drug foll…

Healthy Volunteers

Estimated

~$10 – $8,750

Mirum Pharmaceuticals, Inc.NCT07712718

Observational

Supporting High-intensity Interval Training With Mindfulness for Enhancing Childhood Executive Function

The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HII…

Healthy Volunteers

Estimated

~$10 – $6,250

Purdue UniversityNCT06270589

Observational

Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans

There are a number of disorders of the brain that have limited treatment options, such as chronic pain, addiction, and major depression. A new technology has e…

Healthy Volunteersno Condition, Basic Science

Estimated

~$10 – $6,250

Massachusetts Institute of TechnologyNCT07508722

Phase 1

Supporting High-intensity Interval Training With Mindfulness for Enhancing Childhood Executive Function

The goal of this randomized controlled trial is to learn about the effect of a 12-week school-based intervention combining mindfulness with high-intensity inte…

Healthy Volunteers

Estimated

~$10 – $6,250

Purdue UniversityNCT06258941

Collection of Blood, Bone Marrow, Urine, and/or Tissue Samples From Patients With Solid Tumors, Hematological Malignancies or Non-Malignant Hematologic Disorders or HLA Compatible Family Members

This study will collect biological samples for use in research experiments aimed at better understanding the clinical features of certain diseases. The specime…

NeoplasmsHematologic NeoplasmsHealthy Volunteers

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT00071045