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121 recruiting studies matching your filters

An Open-Label, Single Dose Study to Determine the Metabolism and Excretion of [14C]E2086 in Healthy Male Participants

The primary purpose of this study is to determine the metabolism and excretion of \[14C\]E2086 in healthy male participants.

Healthy Volunteers

Estimated

~$10 – $8,750

Eisai Inc.NCT07308236

Phase 1

A Phase 1, Randomized, Double-blind, Positive-controlled, Placebo-controlled, 4-Period Crossover, Thorough QT/QTc Study to Evaluate the Effect of Multiple Doses of BMS-986278 on Cardiac Repolarization in Healthy Participants

The purpose of this study is to evaluate the effect of BMS-986278 on the cardiac repolarization in healthy participants.

Healthy Volunteers

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07422298

Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide

Background: Proteins are essential to the health and structure of the cells that make up body tissues. Most proteins become damaged over time and are replaced…

Healthy Volunteers

Estimated

~$10 – $675

National Institute on Aging (NIA)NCT06269653

Phase 1

A Phase 1, Open-label, 2-part, Fixed-sequence, Crossover Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Pharmacokinetics of AR-LDD (BMS-986365) in Healthy Adult Male Participants

The purpose of this study is to evaluate the effect of Itraconazole and Rifampin on the drug levels of AR-LDD (BMS-986365) in healthy adult male participants.

A Phase 1, Open-label, Randomized, Crossover Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 Tablet(s) in Healthy Participants

This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation…

Healthy Volunteers

Estimated

~$10 – $8,750

Genentech, Inc.NCT07329972

Phase 2

Evaluation of Ultralow Dose PET Imaging for Detecting Amyloid Tracer Uptake

The goal of this clinical trial is to evaluate an investigational ultralow dose Positron Emission Tomography (PET) imaging technique for Alzheimer's disease, m…

Alzheimer DiseaseMild Cognitive ImpairmentDementia+1 more

Estimated

~$10 – $7,500

Akiva MintzNCT07012993

Observational

Temporal Interference Methods for Non-invasive Deep Brain Stimulation

In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal…

Healthy Volunteers

Estimated

~$10 – $6,250

Indiana UniversityNCT07339072

Phase 4

A Phase IV, Open-label, Single-group Study Evaluating KarXT Concentrations in the Breast Milk and Plasma of Healthy Lactating Female Participants

The purpose of this study is to characterize the PK of xanomeline and trospium in breast milk and plasma in healthy lactating female participants, following mu…

Healthy Volunteers

Estimated

~$10 – $8,750

Karuna Therapeutics, Inc., a Bristol Myers Squibb companyNCT07257120

Observational

Kaempferol Absorption and Pharmacokinetics Evaluation (K.A.P.E.)

This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plan…

No DiseaseMitochondria HealthLongevity+2 more

Estimated

~$10 – $6,250

University of PittsburghNCT07322406

Phase 1

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Doses of MT-701 in Healthy Participants

First-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple doses of MT-701 in healthy particip…

Healthy Volunteers

Estimated

~$10 – $8,750

Mirador Therapeutics, Inc.NCT07396909

Toward Precision Radiotherapy: Physiological Modeling of Respiratory Motion Based on Ultra-quality 4D-MRI

The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic res…

Healthy VolunteersLiver CancerLung Cancer

Estimated

~$10 – $750

University of VirginiaNCT04657042

Phase 1

A Phase 1, Double-blinded, Placebo-controlled Study of Single Ascending Doses of NNC4004-0002 in Adults With Asymptomatic Hyperuricemia

This study will evaluate an investigational drug called NNC4004-0002. "Investigational" means NNC4004-0002 has not been approved for sale/ for clinical use or …

Healthy VolunteersHyperuricemia

Estimated

~$10 – $7,500

Novo Nordisk A/SNCT06859073