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135 recruiting studies matching your filters

A Phase I Study of Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Other Hematologic Malignancies

Background: Blood cancers (such as leukemias) can be hard to treat, especially if they have mutations in the TP53 or RAS genes. These mutations can cause the …

Malignancy, HematologicNeoplasms, HematologicNeoplasms, Hematopoietic+8 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06904066

Phase 2

Phase II Haploidentical Hematopoietic Stem Cell Transplantation for Participants With Germline RUNX1 Associated Hematologic Malignancies

Background: Some blood cancers can be caused by germline variants (changes) in a person s RUNX1 gene. Germline variants are genetic inherited changes a person…

Core Binding Factor Alpha SubunitsHematologic NeoplasmsLeukemia+1 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07524530

Observational

Mosaic: RCT of a Digital Health Intervention for English- and Spanish-speaking Stem Cell Transplant Recipients

The goal of this clinical trial is to learn if using an intervention website (Mosaic) improves selected patient-reported outcomes in adult blood cancer patient…

Hematologic MalignancyStem Cell TransplantBone Marrow Transplant+4 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT06960993

Gene Therapy Follow up Protocol for Subjects Previously Enrolled in CAR T-Cell Studies

Background: \- Gene therapy is a way to treat or prevent disease using genes. It is monitored very closely by regulators because there can be long-term, unexp…

Lyphoma, B-CellLeukemia, B-cellMultiple Myeloma+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT02473757

Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

Background: Researchers seek ways to study people s medical problems in order to teach and further general knowledge. The ability to assess and treat people w…

Wide Spectrum of DiseasesHematologic Diseases

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT04450927

Phase 3

Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor-T Cell (CAR-T)Therapy

The overall purpose of this randomized control trial (RCT) is to determine the clinical effect of a multilevel, RPM-enhanced intervention during and after comp…

Hematologic Malignancies

Estimated

~$50 – $1,500

Actual pay is set by the research site.

City of Hope Medical CenterNCT07186192

The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research

Acquire residual human specimens and/or samples from patient samples which were sent for testing at LabPMM, LLC for Clinical Research

Hematologic Diseases

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Invivoscribe, Inc.NCT06222164

Immune Profiling for Cancer Immunotherapy Response

In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylatio…

CancerTumor, SolidHematologic Malignancy+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Dartmouth-Hitchcock Medical CenterNCT06116032

Observational

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

This clinical trial tests next generation sequencing (NGS) for the detection of precursor features of pre-myeloid cancers and bone marrow failure syndromes. NG…

Myeloid MalignancyInherited Bone Marrow Failure SyndromeClonal Expansion+10 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT02958462

Observational

Planning Advance Care Together (PACT) to Improve Engagement in Advance Care Planning

This clinical trial tests a new mobile health application (app) called Planning Advance Care Together (PACT) to help people with cancer talk about and plan for…

Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Hematologic Malignancy+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT04515810

Phase 1

A Phase 1/2, Multicenter, Open-Label, Multi-Cohort, First-in Human Trial of DS3790a, a DXd-ADC Targeting CD37, for Hematological Malignancies

This clinical trial is designed to assess the safety, preliminary efficacy, and pharmacokinetics (PK) of DS3790a monotherapy and combination regimens in partic…

Hematological MalignanciesB-cell Non-Hodgkin Lymphoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Daiichi SankyoNCT07220616

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

Background: After an allogeneic hematopoietic stem cell transplant (HSCT), the donor genome is found in the recipient s circulation and tissues. Post-HSCT re…

LeukemiaLymphomaHematologic Malignancy

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06856226