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127 recruiting studies matching your filters

Umbilical Cord Blood Transplantation From Unrelated Donors

This study is being done to determine how long it takes for the engraftment (recovery of blood cell counts) of umbilical cord stem cells and also how often eng…

Acute LeukemiaImmune Deficiency DisorderCongenital Hematological Disorder+7 more

Estimated

~$10 – $750

University of RochesterNCT03016806

Phase 1

An Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma

This is a multi-center, open-label study to evaluate the safety, pharmacokinetics (PK), and anti-cancer activity of oral administration of emavusertib alone or…

Relapsed Hematologic MalignancyRefractory Hematologic MalignancyRelapsed Primary Central Nervous System Lymphoma+1 more

Estimated

~$10 – $8,750

Curis, Inc.NCT03328078

Observational

Allogeneic Hematopoietic Stem Cell Transplantation From an HLA-partially Matched Related or Unrelated Donor After TCR αβ+T Cells/CD19+ B Cell Depletion in Children and Young Adults Affected by Malignant or Non-Malignant Hematological Disorders

The purpose of the CliniMACS® TCRαβ-Biotin System and CliniMACS® CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unre…

Hematologic Diseases

Estimated

~$10 – $7,500

Alice BertainaNCT04249830

Mayo Clinic Radiotherapy Patient Outcomes Registry and Biobanking Study

To collect and analyze specimens that will correlate with clinical outcomes such as acute and late toxicities, quality of life, local control, and survival of …

Solid TumorsHematologic Malignancies

Estimated

~$10 – $750

Mayo ClinicNCT02457962

A Long-Term Follow-up Study for Subjects Previously Treated With A Century Therapeutics Cellular Therapy Product

This study is designed to collect long-term safety and survival data from participants previously treated in an eligible Century-sponsored index trial. This is…

Hematological MalignancySolid Tumor Malignancy

Estimated

~$10 – $1,050

Century Therapeutics, Inc.NCT05768269

Phase 2

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

To learn if the combination of pirtobrutinib (also called LOXO-305) and venetoclax can help to control mantle cell lymphoma (MCL) that is relapsed (has come ba…

Mantle Cell LymphomaNon Hodgkin LymphomaHematologic Malignancy

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05529069

Phase 1

A Phase I/II, Open-label, Multicenter Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Anti-GPRC5D CAR-T Cell Product (OriCAR-017) in Subjects With Relapsed/Refractory Multiple Myeloma.

The is a first clinical study for Oricell Therapeutics Inc. in the United States to evaluate the safety, PK, PD and preliminary efficacy of our anti-GPRC5D cel…

Neoplasms, Plasma CellNeoplasms by Histologic TypeNeoplasms+11 more

Estimated

~$10 – $8,750

OriCell Therapeutics Co., Ltd.NCT06271252

The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research

Acquire residual human specimens and/or samples from patient samples which were sent for testing at LabPMM, LLC for Clinical Research

Hematologic Diseases

Estimated

~$10 – $1,050

Invivoscribe, Inc.NCT06222164

Observational

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy: The PEACE Study

The goal of this study is to determine whether a palliative care intervention (PEACE) can improve the quality of life and experiences of participants with Lymp…

Hematologic MalignancyBlood CancerLymphoma+2 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05646576

Phase 3

A Phase 3b Study to Evaluate Efficacy and Safety of a Single Dose of Autologous CRISPR Cas9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells (CTX001) in Subjects With Transfusion-Dependent β-Thalassemia or Severe Sickle Cell Disease

This is a single-dose, open-label study in participants with transfusion-dependent β-thalassemia (TDT) or severe sickle cell disease (SCD). The study will eval…

Beta-ThalassemiaThalassemiaHematologic Diseases+4 more

Estimated

~$10 – $8,750

Vertex Pharmaceuticals IncorporatedNCT05477563

Observational

Intervention Strategies to Improve Cognitive Functioning in Hematologic Cancer Survivors After Hematopoietic Cell Transplantation

A pilot study to evaluate feasibility of enrollment of patients in an intervention to improve neurocognitive function in hematopoietic cell transplantation (HC…

Cognitive ImpairmentHematologic NeoplasmsHematopoietic Cell Transplant

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT03094026

UWCCC Precision Medicine Molecular Tumor Board Registry

This study seeks to evaluate the clinical utility of the Precision Medicine Molecular Tumor Board, and to track patient outcomes.

Hematologic NeoplasmsSolid Neoplasm

Estimated

~$10 – $750

University of Wisconsin, MadisonNCT03023202