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43 recruiting studies matching your filters

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy: The PEACE Study

The goal of this study is to determine whether a palliative care intervention (PEACE) can improve the quality of life and experiences of participants with Lymp…

Hematologic MalignancyBlood CancerLymphoma+2 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05646576

Mechanisms of Disease Relapse/Resistance in CAR T Therapy for Hematologic Malignancies

The primary purpose of this IRB protocol is to perform immune profiling focusing on the measurement of Myeloid derived suppressor cells (MDSCs) over time in pa…

Hematologic Malignancy

Estimated

~$10 – $750

Duke UniversityNCT05397132

A Phase II Trial of Reduced Intensity Fludarabine and Total Body Irradiation-Based Conditioning Prior to Haplo-Identical Transplantation for Patients With Hematologic Malignancies

This trial will evaluate the safety and efficacy of RIC HIDT transplant protocol following fludarabine and intermediate-dose TBI 800 cGy utilizing PBSC as the …

Hematologic Malignancy

Estimated

~$10 – $750

Northside Hospital, Inc.NCT05417971

Phase 1

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

The study participant has one of the following blood cancers: acute myelogenous leukemia (AML)/myelodysplastic syndrome (MDS), acute lymphoblastic leukemia (B-…

Hematologic MalignancyALL, ChildhoodAML, Childhood+2 more

Estimated

~$10 – $6,250

St. Jude Children's Research HospitalNCT06326463

Phase 1

A Phase I Study of Tagraxofusp With or Without Chemotherapy in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Tagraxofusp is a protein-drug conjugate consisting of a diphtheria toxin redirected to target CD123 has been approved for treatment in pediatric and adult pati…

Hematologic MalignancyAMLALL+8 more

Estimated

~$10 – $7,500

Therapeutic Advances in Childhood Leukemia ConsortiumNCT05476770

Observational

Reducing Persistent Fatigue Following Hematopoietic Stem Cell Transplantation

The purpose of this study is to assess whether a cognitive-behavioral therapy (CBT) for fatigue intervention is acceptable, feasible, and effective at managing…

Hematologic CancerHematologic Malignancy

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05715047

Observational

Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation

Primary PC - or training HCT clinicians to deliver PC domains as part of routine practice - is an alternative model of supportive care. We have developed Senti…

Hematopoietic Cell TransplantHematologic Malignancy

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06676852