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3 recruiting studies matching your filters
Phase 1
TACTICAL: TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT
The purpose of this study is to test the feasibility and safety of early cessation of tacrolimus following allogeneic hematopoietic cell transplantation (HCT).…
GVHDHematopoietic Cell Transplantation (HCT)Acute Myeloid Leukemia (AML)+4 more
Stanford UniversityNCT07302776
Phase 1
Phase 1 Trial for Patients With Advanced Hematologic Malignancies Undergoing Reduced Intensity Allogeneic HCT With a T-cell Depleted Graft With Infusion of Conventional T-cells and Regulatory T-cells
Reduced intensity conditioning (RIC) has emerged and been increasingly adopted as a modality to allow preparative conditioning pre transplant to be tolerated b…
Allogeneic Hematopoietic Cell Transplantation (HCT)Advanced Hematologic MalignanciesAcute Leukemia+3 more
Stanford UniversityNCT05088356
Phase 1
A Phase I Study to Evaluate the Safety and Maximum Tolerated Dose of Momelotinib Durind and Following Hematopoietic Cell Transplantation for Patients With Myelofibrosis
This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hema…
MyelofibrosisHematopoietic Cell Transplantation (HCT)
Massachusetts General HospitalNCT07104799