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3 recruiting studies matching your filters
Phase 2
Study of TCR Alpha Beta T-Cell and CD19 B-Cell Depletion for Hematopoietic Cell Transplantation From Haploidentical Donors in the Treatment of Non-Malignant Hematological Disorders in Children
This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is s…
Hemoglobinopathy (Disorder)Severe Aplastic AnemiaBone Marrow Failure Syndrome
Estimated
~$10 – $6,250
Johns Hopkins All Children's HospitalNCT04356469
A Long-term Follow-up Study in Patients With Hemoglobinopathy Who Received Autologous CD34+ Edited Hematopoietic Stem Cells
This is a Long-term Follow-up (LTFU) study in patients who received BEAM-101 in the parent study (Study BTX-AUT-001). Eligible patients who received BEAM-101 w…
HemoglobinopathySickle Cell Disease
Estimated
~$10 – $1,050
Beam Therapeutics Inc.NCT07373639
Phase 1
Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling
Background: Sickle cell disease (SCD) is an inherited disorder of the blood. SCD causes red blood cells (RBCs) to die early. This can lead to a shortage of he…
Sickle Cell DiseaseThalassemiaHemoglobinopathy
Estimated
~$10 – $5,625
National Heart, Lung, and Blood Institute (NHLBI)NCT06313398