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A Phase 3, Randomized, Double-blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Engasertib in Subjects With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT)

The primary objective of this trial is to assess the efficacy of engasertib 40 mg once daily (QD) in reducing the frequency of epistaxis compared to placebo QD…

Hereditary Hemorrhagic Telangiectasia

Estimated

~$10 – $8,750

Vaderis Therapeutics AGNCT07743671

Phase 1

A Randomized, Placebo-Controlled, Double-Blind, Proof-of-Concept Study of ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)

This is a 2-part study evaluating ATV-1601 in participants with moderate to severe HHT. Part 1 is a randomized, double-blind, placebo-controlled study evaluati…

Hereditary Hemorrhagic Telangiectasia (HHT)Osler Weber Rendu Disease

Estimated

~$10 – $8,750

Atavistik Bio, IncNCT07601425

Phase 1

A Phase I Trial of TOR-582, a Topical Sirolimus-based Treatment for Epistaxis in Adults With Hereditary Hemorrhagic Telangiectasia

People with hereditary hemorrhagic telangiectasia (HHT) often experience frequent and severe nosebleeds that can disrupt daily life and lead to anemia, medical…

Hereditary Hemorrhagic Telangiectasia (HHT)Epistaxis

Estimated

~$10 – $6,250

Columbia UniversityNCT07667413

CHORUS: Comprehensive HHT (Hereditary Hemorrhagic Telangiectasia) Outcomes Registry of the United States

The Comprehensive HHT Outcomes Registry of the United States (CHORUS) is an observational registry of patients diagnosed with Hereditary Hemorrhagic Telangiect…

Hereditary Hemorrhagic TelangiectasiaArteriovenous MalformationsTelangiectasia+4 more

Estimated

~$10 – $1,125

Cure HHTNCT06259292