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4 recruiting studies matching your filters
Phase 1
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
High-grade gliomas (HGGs) are among the most aggressive and treatment-resistant brain tumors. Immunotherapy with checkpoint inhibitors like nivolumab has shown…
Brain CancerHGGGlioma+4 more
Estimated
~$10 – $7,500
Eben RosenthalNCT07210632
Phase 2
Phase 2 Trial of G207 + 5 Gy Radiation for Children With High-Grade Gliomas
The goal of this clinical research study is to learn about the safety and effects of G207 combined with radiation therapy in patients with recurrent or progres…
High Grade Gliomas
Estimated
~$10 – $6,250
M.D. Anderson Cancer CenterNCT07649070
Phase 1
A Phase I/II Study of an AAV-1 Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
The goal of this clinical trial is to first define the Safety and Optimal Biological Dose (OBD) of study drug TGX-007 and to then further investigate the safet…
Glioblastoma (GBM)High Grade GliomasRecurrent Glioblastoma+1 more
Estimated
~$10 – $8,750
Trogenix ltdNCT07346144
Phase 1
JACOB: Joint Administration of cDNA for TP53, checkpOint Inhibition and Boost/Hypofractionated Radiation. A Phase 0/1 Study in Children With Recurrent, Progressive or Refractory CNS Malignancies.
This clinical trial is studying a drug called SGT-53 along with radiation and another drug called Nivolumab. It's for children with brain tumors that have come…
CNS MalignanciesMedulloblastoma RecurrentATRT Recurrent+4 more
Estimated
~$10 – $5,625
Children's National Research InstituteNCT07017816