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29 recruiting studies matching your filters

NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices

This is an early study of a catheter-based minimally invasive procedure called SESAME to slice thick heart muscle as described below. Excessively-thick heart …

Hypertrophic CardiomyopathyLeft Ventricular Outflow ObstructionSystolic Anterior Motion

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT07806149

Risk Stratification of Ischemic and Non-ischemic Cardiomyopathies in Racial and Ethnic Minority Groups in the Bronx - Cardiovascular Multimodality Imaging Study

Determining the etiology of cardiomyopathy is of high clinical importance for optimal treatment strategy and prediction of prognosis. There is increased risk f…

Non-ischemic CardiomyopathyCardiomyopathiesHypertrophic Cardiomyopathy+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Montefiore Medical CenterNCT06610019

Phase 4

Comparison of Remimazolam Versus Propofol for Monitored Anesthetic Care in Elective Fractional Ablative CO₂ Laser

This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for…

Burn ScarHypertrophic ScarringProcedural Sedation

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Medical University of South CarolinaNCT07213544

Pediatric Cardiomyopathy Mutation Analysis

The goal of this protocol is to obtain information from individuals with cardiomyopathy and from their families in order to elucidate the molecular genetics of…

CardiomyopathiesDilated CardiomyopathyHypertrophic Cardiomyopathy+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT02432092

Phase 3

A Phase 3, Multi-region, Multi-center, Randomized, Double-blind, Active-Comparator-Controlled Trial to Evaluate the Efficacy and Safety of BHB-1893 Compared to Metoprolol in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

The main purpose of this trial is to find out whether BHB-1893 works better than metoprolol in adults with symptoms of obstructive hypertrophic cardiomyopathy …

Cardiomyopathy, Hypertrophic Obstructive

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Braveheart Bio, Inc.NCT07755904

Phase 2

A Follow-Up, Open-Label, Research Evaluation of Sustained Treatment With Aficamten (CK-3773274) in Hypertrophic Cardiomyopathy (HCM)

The purpose of this study is to collect long-term safety and tolerability data for aficamten.

Symptomatic Hypertrophic Cardiomyopathy (HCM)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

CytokineticsNCT04848506

Real-World Camzyos Patient Reported OutcoMes Through PAtient SurveyS in Hypertrophic CardioMyopathy (COMPASS-HCM): A Prospective Longitudinal Study

This real-world study will assess changes in health status among participants with symptomatic obstructive hypertrophic cardiomyopathy who are treated with mav…

Obstructive Hypertrophic Cardiomyopathy

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Bristol-Myers SquibbNCT06551129

Observational

Towards Bridging Generalists to Subspecialists With Large Language Models

This study evaluates the impact of large language models (LLMs) versus traditional decision support tools on clinical decision-making in cardiology. General ca…

Hypertrophic Cardiomyopathy (HCM)CardiomyopathyGenetic Disease+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT06935253

Deliver Insights in Hypertrophic Cardiomyopathy and Observational Outcomes in Real World: United States and European Prospective Registry Study

This registry evaluates patient characteristics, real-world treatment patterns, and short- and long-term outcomes in a population of patients in the United Sta…

Obstructive Hypertrophic Cardiomyopathy

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Bristol-Myers SquibbNCT05489705

A Non-interventional Observational Study of the Sustained Use of Prolaio Digital Health Devices to Monitor the Natural History of Chronic Cardiovascular Conditions in Ambulatory Patients

This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.

Cardiovascular Disease (CVD)Heart FailureAortic Stenosis+9 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

ProlaioNCT07420907

Phase 4

Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy

This is an investigator-initiated two-center study. The goal of this study is to investigate the feasibility, safety and efficacy outcomes of a seamless transi…

Hypertrophic Cardiomyopathy (HCM)

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Oregon Health and Science UniversityNCT07600177

Phase 1

Zinc Oxide Versus Petrolatum Following Skin Surgery: A Head-to-head, Prospective, Split-scar Study

Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than o…

Surgical IncisionSurgery--ComplicationsSurgical Wound+3 more

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Melissa Pugliano-MauroNCT03561376