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29 recruiting studies matching your filters

The Application of Preoperative Silicone Ointment and Its Effect on Wound Healing

Optimal scar healing is of great importance to patients, especially following surgery of the head and neck. This study evaluates the effectiveness of preoperat…

Wound HealScarScar, Hypertrophic+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT05461157

Observational

The EXerCise traIning To rEcovery in HCM Trial

The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual p…

Hypertrophic Cardiomyopathy

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT05818605

Observational

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.

Acne Scars - Mixed Atrophic and HypertrophicHyperpigmentationLaser-Induced Hyperpigmentation

Estimated

~$10 – $750

Actual pay is set by the research site.

Montefiore Medical CenterNCT05362929

Mavacamten Pregnancy Surveillance Program

The purpose of this observational pregnancy safety study is to assess maternal, fetal, and infant outcomes after exposure to mavacamten at any time during preg…

BreastfeedingHypertrophic CardiomyopathyPregnancy Related

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Bristol-Myers SquibbNCT05939700

Phase 1

First-in-Human, Open-Label, Safety, Tolerability, Dose-Finding, Pharmacodynamic and Cardiac Transgene Expression Study of TN-201, a Recombinant Adeno-associated Virus Serotype 9 (AAV9) Containing Myosin Binding Protein C Transgene, in Adults With MYBPC3 Mutation-associated Hypertrophic Cardiomyopathy (HCM)

This is a first-in-human, non-randomized, open-label study designed to evaluate the safety, tolerability, and pharmacodynamics (PD) of TN-201 in adult patients…

Hypertrophic Cardiomyopathy

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Tenaya TherapeuticsNCT05836259

Phase 1

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

The goal of this clinical trial is to learn if sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, works to treat symptomatic, nonobstructive hypertrophic cardiom…

Hypertrophic Cardiomyopathy Without Obstruction

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of PennsylvaniaNCT06433050

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Primary objective: To identify older adults with transthyretin cardiac amyloidosis (ATTR-CA) early in the course of the illness, at a time when disease modify…

Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT06034405

Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias (Long QT Syndrome, Brugada Syndrome, CPVT and Early Repolarization Syndrome)

Human induced pluripotent stem cells (hiPSCs) have driven a paradigm shift in the modeling of human disease; the ability to reprogram patient-specific cells ho…

Inherited Cardiac ArrythmiasLong QT Syndrome (LQTS)Brugada Syndrome (BrS)+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Johns Hopkins UniversityNCT02413450

Phase 1

A Phase 1/2, Open-Label Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of Intravenous ATR 1072 for the Treatment of PRKAG2 Syndrome

ATR 1072 is an investigational medicine being studied in adults with PRKAG2 Syndrome. This study will evaluate the safety of ATR 1072 and how the body processe…

Cardiac GlycogenosisCardiomyopathyHypertrophic+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Atrium TherapeuticsNCT07738107

Phase 3

Topical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot Study

The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections…

Keloid ScarsHypertrophic Scars

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Sonal ChoudharyNCT07336368

Observational

A Randomized Split-Wound Clinical Trial Comparing SYLKE Silk Fibroin Dressing to Standard Adhesive Dressings in Abdominoplasty and Panniculectomy Patients

Include primary, secondary, and exploratory objectives. Primary Goal: To compare the effects of a silk fibroin-based dressing versus standard postoperative dr…

Hypertrophic Surgical ScarMedical Adhesive Related Skin Injury

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Missouri-ColumbiaNCT07878390

Coronary Flow Reserve in oHCM Patients Before and After 12 Months of Standard-of-care Mavacamten Treatment as Assessed by PET/CT

The goal of this observational study is to measure the effect of mavacamten treatment on blood flow in the heart muscle (myocardium) in patients with obstructi…

Obstructive Hypertrophic Cardiomyopathy

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Michael AyersNCT06023186