This phase II trial gathers information on the feasibility, safety, and effect of giving methotrexate, erlotinib, and celecoxib in treating head and neck cance…

Metastatic Oral Cavity CarcinomaRecurrent Oral Cavity CarcinomaStage IVC Lip and Oral Cavity Cancer AJCC v8+15 more

~Estimated

~$10 – $6,250

Mayo ClinicNCT06997068

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often …

HNSCCOral Cavity CancerOropharynx Cancer+2 more

~Estimated

~$10 – $750

University Hospital FreiburgNCT05337631

Phase 2

A Phase II Study of Sacituzumab Govitecan in Combination With Cetuximab in Patients With Recurrent Metastatic HNSCC That Has Progressed After First-Line Therapy

The purpose of this study to find out whether sacituzumab govitecan in combination with cetuximab is an effective and safe treatment approach for people with r…

Squamous Cell Carcinoma of Head and NeckSinus CancerNasal Cavity Cancer+9 more

~Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT07063212