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31 recruiting studies matching your filters

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis: An International Comparative Effectiveness Research Project

Fluid-unresponsive hypotension needing cardiotropic drug treatment is a serious complication in very preterm neonates with suspected late-onset sepsis (LOS; de…

Late-Onset Neonatal SepsisExtreme PrematurityNeonatal Hypotension

Estimated

~$10 – $750

Mount Sinai Hospital, CanadaNCT05347238

Observational

Randomized, Controlled, Double-blind Trial of Lower Versus Higher Dialysate Bicarbonate in Hospitalized Maintenance Hemodialysis Patients

QTc prolongation and premature ventricular contractions (PVCs) are common in hemodialysis (HD) patients and are associated with sudden cardiac death. It is kn…

Peri-dialytic Cardiac RhythmsIntradialytic HypotensionElectrolyte Changes+2 more

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT05814146

Phase 4

Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery (ANG-First Trial)

The purpose of this research is to evaluate the use of Angiotensin II in patients with low blood pressure post-surgery. Your information will be collected for …

Vasodilatory Hypotension During or After Cardiac Surgery

Estimated

~$10 – $6,250

University of Maryland St. Joseph Medical CenterNCT06487585

Phase 3

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor A Randomized, Double-blind, Placebo-controlled, Cross Over Explorative Study

Currently, there is no medication available to adequately treat patients undergoing hemodialysis who are suffering from intradialytic hypotension (IDH). Medica…

Intradialytic Hypotension

Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT05834777

The CurePSP Genetics Program

This study is an observational, prospective genetic study. It aims to obtain DNA for research and testing from patients with PSP, CBS, MSA, and related neurolo…

PSPPSP - Progressive Supranuclear PalsyCorticobasal Syndrome+17 more

Estimated

~$10 – $750

Massachusetts General HospitalNCT06647641

Phase 4

Phase 4 Open Label Study to Determine Pharmacokinetics of Phenylephrine and Pharmacodynamic Effects on BP Via IV Admin of Phenylephrine Hydrochloride Inj in Ped Subjects (≥12 to 16 Years of Age) Undergoing Gen and Neuraxial Anesthesia

The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased b…

Hypotension

Estimated

~$10 – $8,750

West-Ward PharmaceuticalNCT02323399

Phase 1

The Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure Aim 2 of RDCRN (Rare Diseases Clinical Research Network) Project 2

The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low…

Autonomic FailurePure Autonomic FailureMultiple System Atrophy+2 more

Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT02897063