Browse Studies — Arctuva

Phase 1

A Study of RM-718 Weekly Formulation in Healthy Subjects With Obesity and in Patients With Obesity Due to MC4R Impairment

The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairme…

Hypothalamic ObesityPrader-Willi SyndromePWS

Estimated

~$10 – $8,750

Rhythm Pharmaceuticals, Inc.NCT06239116

Phase 4

The Effects of Tirzepatide in Young Adults With Prader-Willi Syndrome, Hypothalamic Obesity and General Non-Syndromic Obesity

This research study is comparing the effectiveness of a weight loss medication called Tirzepatide in young adults with Prader-Willi Syndrome and/or hypothalami…

Prader-Willi SyndromeHypothalamic ObesityObesity/Therapy

Estimated

~$10 – $7,500

Grace KimNCT06901245

Phase 3

A Phase 3, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Setmelanotide in Patients With Acquired Hypothalamic Obesity

This is a sub-study of Study RM-493-040 (NCT05774756). The goal of this sub-study is to learn how well Setmelanotide works to improve weight reduction, hunger…

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more

Estimated

~$10 – $8,750

Rhythm Pharmaceuticals, Inc.NCT06760546

Phase 2

Phentermine/Topiramate in Children, Adolescents, and Young Adults With Hypothalamic Obesity: a Pilot and Feasibility Study

Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant for…

Hypothalamic ObesityHypothalamic TumorCraniopharyngioma

Estimated

~$10 – $6,250

Seattle Children's HospitalNCT06299891