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Ventricular Tachycardia Substrate Mechanisms Revealed by Local Repolarization and Conduction Parameters
The purpose of this study is to understand why certain hearts have ventricular arrhythmias and help identify areas of the heart that cause arrhythmias. There i…
Safety and Feasibility of the MyokinE100 System in ICU Settings to Mitigate ICU Acquired Weakness
The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in th…
A Phase 3, Single-arm, Open-label Extension Study to Evaluate the Safety of Finerenone in Addition to Standard of Care, in Pediatric Heart Failure Patients, From Birth to 18 Years of Age, With Left Ventricular Systolic Dysfunction (LVSD)
Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD). Heart fai…
Compassion Strikes Back: Improving Dyadic Quality of Life for LVAD Patients and Caregivers
Research has shown that LVAD patients and their caregivers typically experience increased mental health concerns and decreased quality of life following LVAD i…
Personalized Ventilator Settings for Patients on ECMO (PEEPECMO)
While mechanical ventilation can be used to sustain life in those with lung injury, it, can further worsen lung injury or prevent lung healing resulting in hig…
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimen…
The Early Feasibility Study of the Transcatheter Tricuspid Valve Replacement System Transfemoral System
The objective of this early feasibility study is to gain early clinical insight into the performance of the Intrepid transcatheter tricuspid valve replacement …
A Phase II Study of Brentuximab Vedotin Plus Bendamustine for Relapsed/Refractory Follicular Lymphoma
This phase II trial investigates how well brentuximab vedotin and bendamustine work in treating patients with follicular lymphoma that has come back (relapsed)…
MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation (MAGNETIC-AF)
The purpose of this research study is to find out if the use of magnesium in addition to Metoprolol, a rate controlling medication that you would be offered in…
Effectiveness of T-DXd Across HER2-positive Solid Tumors in Patients Who Have Received Prior Systemic Treatment and Have no Satisfactory Alternative Treatment Options: A Hybrid Observational Study
This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have…
A Phase 2 Open Label Study of XL092 as First Line Therapy in Radioiodine Refractory Differentiated Thyroid Cancer
This phase II trial tests how well XL092 works for the treatment of patients with differentiated thyroid cancer that has not responded to previous treatment wi…
Cellular and Physical Function Outcomes Leading to Failed Muscle Recovery After Critical Illness/Muscle and Physical Functional Recovery After Acute Critical Illness
The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to r…