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Phase 2
A Phase 2 Trial of All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma
This is a Phase II study of the combination of All-Trans Retinonic Acid (ATRA) and PD-1 inhibition (Retifanlimab) in patient with recurrent IDH-mutant glioma. …
GliomaIDH MutationAstrocytoma+1 more
Stephen Bagley, MD, MSCENCT05345002
Phase 1
Early Phase 1 Window of Opportunity Study of Oral DSP-0390 in Gliomas
This study focuses on determining the pharmacokinetic and pharmacodynamic effect of DSP-0390 in brain and blood from patients with IDH-mutant glioma undergoing…
Glioma, MalignantIDH Mutation
Washington University School of MedicineNCT06636162