Find your next paid study

National Institute of Allergy and Infectious Diseases (NIAID)NCT00246857

~$10 – $675

Screening and Baseline Assessment of Patients With Abnormalities of Immune Function

This study will evaluate patients with abnormal immune function that results in recurrent or unusual infections or chronic inflammation. This may include inher…

Chronic Granulomatous Disease (CGD)X-Linked Severe Combined Immune Deficiency (XSCID)Leukocyte Adhesion Deficiency 1 (LAD)+1 more

National Institute of Allergy and Infectious Diseases (NIAID)NCT00128973

~$10 – $675

Phase 3

A Phase 3, Prospective, Open-label, Multicenter, Single-arm Study to Investigate the Efficacy, Safety, and Pharmacokinetics of IgPro20 in Subjects With Secondary Immune Deficiency Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies

This is a prospective, multicenter, open-label, single-arm study to assess the efficacy, safety, and pharmacokinetics (PK) of IgPro20 in adults with hematologi…

Secondary Immune Deficiency

Epstein-Barr VirusCytomegalovirus InfectionsAdenovirus+2 more

~$10 – $7,500

CSL BehringNCT07648264

Phase 1

Single Center Phase I Study of Adoptive Immunotherapy of Refractory Viral Infection With ex Vivo Expanded Rapidly Generated Virus Specific T (R-MVST) Cells for Immunodeficient Children and Young Adults

The primary objective is to determine the safety and feasibility of administering R-MVST cells to patients with refractory viral reactivation and/or symptomati…

~$10 – $7,500

Monica BhatiaNCT06926894

Primary Immune Deficiency DisordersMetabolic Disease

Study of TCR Alpha Beta T-Cell and CD19 B-Cell Depletion for Hematopoietic Cell Transplantation From Haploidentical Donors in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children

This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is s…

Johns Hopkins All Children's HospitalNCT04414046

Bone Marrow FailureHemoglobinopathiesPrimary Immune Deficiency (PID)+4 more

A Phase II Prospective Study Evaluating Selective Depletion of CD45RA+ (Naïve) T Cells (TND) From Peripheral Blood Stem Cell (PBSC) Grafts for Prevention of Graft Versus Host Disease (GVHD) in Non-Malignant Diseases (NMDs)

This phase II trial investigates how well a naive T cell depleted graft work for the reduction of graft versus host disease in patients with non-malignant dise…

Fred Hutchinson Cancer CenterNCT07660783

Observational

Let's Get REAL: A Pilot Trial of a Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy

The investigators will conduct a pilot feasibility and efficacy trial of a newly developed family health communication tool (called Let's Get REAL) in increasi…

Hematologic MalignancySolid TumorSickle Cell Disease+3 more

Washington University School of MedicineNCT06689800

Observational

Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization

This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as ant…

HIV (Human Immunodeficiency Virus)Clinical Decision Support System (CDSS)Antiretroviral Therapy, Highly Active+4 more

Keck School of Medicine of USCNCT07219862

Epstein-Barr Virus InfectionsPrimary Immune Deficiency Disorder

A Pilot Study in the Treatment of Refractory Epstein-Barr Virus (EBV) Infection With Related Donor EBV Cytotoxic T-Lymphocytes in Children, Adolescents and Young Adult Recipients

Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be admin…

New York Medical CollegeNCT03266653

Primary Immune Deficiency DisorderImmune Deficiency DiseaseBone Marrow Failure+7 more

Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures

Phase II prospective trial to assess the rates of donor engraftment using reduced intensity conditioning (RIC) hematopoietic stem cell transplant (HSCT) and po…

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT04232085

AdenovirusPrimary Immune Deficiency Disorder

A Pilot Study in the Treatment of Refractory Adenovirus (ADV) Infection With Related Donor ADV Cytotoxic T-Lymphocytes (ADV-CTLs)in Children, Adolescents and Young Adult Recipients

Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered …

New York Medical CollegeNCT03266627

Biologics And Clinical Immunology Cohort at Sinai

The study team plans to establish a bioregistry of patients receiving biologic therapy as part of their standard treatment at the Mount Sinai Therapeutic Infus…

Immunological DiseaseAutoimmune DiseasesPrimary Immune Deficiency