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20 recruiting studies matching your filters

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome…

InfectionsPneumoniaImmune System Diseases+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT00006150

Phase 2

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Background: Allogeneic blood or marrow transplant is when stem cells are taken from one person s blood or bone marrow and given to another person. Researchers…

Primary T-cell Immunodeficiency DisordersCommon Variable ImmunodeficiencyImmune System Diseases+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT02579967

Phase 1

A Randomized, Double-Masked, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ETHY-001

The primary objective of study is to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ETHY-001 in healthy volunteers and partici…

Thyroid Eye Disease (TED)Graves' DiseaseEye Diseases, Hereditary+11 more

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Ethyreal Bio, Inc.NCT07885605

Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Background: During a transplant, blood stem cells from one person are given to someone else. The cells grow into the different cells that make up the immune s…

Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System Diseases+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04339777

Phase 1

A Phase I/IIa, Single Site, Open-Label, Ascending Dose Study to Evaluate the Safety and Efficacy of OPF-310 [Encapsulated Porcine Islet Cells for Xenotransplantation] in Subjects With Type 1 Diabetes Mellitus

This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tole…

Diabetes Mellitus, Type 1HypoglycemiaIslet Cell Transplantation+14 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Eosinophil Activation and Function in Parasitic Infections and Other Conditions With Increased Tissue or Peripheral Blood Eosinophilia in Humans

This study will investigate how, why and under what conditions eosinophils (a type of white blood cell) become activated and will examine their function in imm…

Immune System DiseasesEosinophiliaHelminthiasis+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001406

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic maligna…

Hematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of Platelets+14 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Phase 2

Thinking Zinc: A Study of Zinc Supplementation to Ameliorate Adverse Effects of Mine Waste Exposure on the Navajo Nation

This is a study to assess the effect of dietary zinc supplementation to mitigate biomarkers of metal toxicity in exposed tribal populations.

DNA DamageImmune System Disorder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of New MexicoNCT03908736

Detection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of Immunity

Background: Immune system and nervous system have significant interaction so that People with immunity diseases can have complications that affect the nervous…

Nervous System DiseaseImmune System Disease

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT06169150

Phase 2

METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

The study is a randomized, double-blind, parallel-group clinical trial to examine the effects of 24 weeks of oral AMX0035 (sodium phenylbutyrate + taurursodiol…

Type 1 Diabetes (T1D)Metabolic DiseasesGlucose Metabolism Disorders+6 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of WashingtonNCT07699380

Phase 1

A Phase 1 Study to Evaluate the Safety of KLN-1010, a Novel, In Vivo Gene Therapy to Generate Anti-B Cell Maturation Antigen (Anti-BCMA) Chimeric Antigen Receptor-T Cells (CAR-T) in Patients With Relapsed and Refractory Multiple Myeloma

The goal of this clinical trial is to evaluate the safety, tolerability, and recommended Phase 2 Dose (RP2D) of KLN-1010 in patients with relapsed or refractor…

Multiple Myeloma in RelapseMyeloma MultipleMultiple Myeloma Progression+11 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Kelonia Therapeutics, Inc.

Protocol for Immunology Specimen Collection From Cancer Patients, Patients With Hematologic Diagnoses, and Healthy Normal Controls

This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study …

Healthy SubjectHematologic and Lymphocytic DisorderHematopoietic and Lymphoid Cell Neoplasm+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Southern CaliforniaNCT03207854