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64 recruiting studies matching your filters

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

This is a phase I/II open label multi-center study in which patients will receive low dose targeted busulfan followed by infusion of autologous CD34+ selected …

Severe Combined Immunodeficiency, X LinkedGene Therapy

Estimated

~$10 – $7,500

David WilliamsNCT03311503

Phase 1

Phase I/II Safety and Efficacy Study of Gene Transfer for Artemis-Deficient Severe Combined Immunodeficiency (ART-SCID) in Newly Diagnosed Patients Using Self-Inactivating Lentiviral Vector (AProArt) to Transduce Autologous CD34 Hematopoietic Cells

This study aims to determine if a new method can be used to treat Artemis-deficient Severe Combined Immunodeficiency (ART-SCID), a severe form of primary immun…

Severe Combined Immunodeficiency

Estimated

~$10 – $5,625

University of California, San FranciscoNCT03538899

Phase 2

A Single-Arm, Open-Label Clinical Phase II Trial of the Safety and Immunogenicity of PDS0101 in People Living With HIV

This study is testing the immunotherapeutic agent, PDS0101, in adults living with HIV who are also infected with human papillomavirus (HPV) type 16. The purpos…

HPV Associated CancersHIV (Human Immunodeficiency Virus)Anal Cancer+2 more

Estimated

~$10 – $6,250

Weill Medical College of Cornell UniversityNCT07090174

Observational

Identifying and Addressing Historical and Structural Drivers of Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men

There is an urgent need to address HIV inequities and disparities in the US, particularly within vulnerable communities such as Hispanic/Latino gay, bisexual, …

Human Immunodeficiency Virus

Estimated

~$10 – $6,250

Wake Forest University Health SciencesNCT06132672

A Prospective Outcomes Study of Pediatric and Adult Patients With Non-Malignant Disorders Undergoing Umbilical Cord Blood, Bone Marrow, or Peripheral Blood Stem Cell Transplantation With a Reduced-Intensity Conditioning Regimen (PRO-RIC)

This is a data collection study that will examine the general diagnostic and treatment data associated with the reduced-intensity chemotherapy-based regimen pa…

Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more

Estimated

~$10 – $1,125

Paul SzabolcsNCT04528355

Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System

The goal of this observational study is to develop, implement, and evaluate a machine learning algorithm-based Hepatitis C Emergency Department (HepC-EnD) scre…

Hepatitis C Virus (HCV)Hepatitis C Virus (HCV) InfectionHIV (Human Immunodeficiency Virus)

Estimated

~$10 – $750

University of FloridaNCT07406490

Phase 4

Low Dose Naltrexone (LDN) for the Treatment of Chronic Neuropathic Pain in Patients With Human Immunodeficiency Virus (HIV), a Prospective, Pragmatic, Open Label Clinical Trial

The increased life expectancy of Patients Living With HIV/AIDS (PLWHA) has increased the need for therapies for chronic conditions, such as chronic pain. Pain …

Human Immunodeficiency VirusChronic Neuropathic Pain

Estimated

~$10 – $6,250

Emory UniversityNCT05537935

Phase 4

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

This study's long-term goal is to improve clinical outcomes among smokers living with HIV (SLWH) by providing smoking cessation interventions in HIV clinical c…

Human Immunodeficiency Virus (HIV)Smoking Cessation

Estimated

~$10 – $6,250

New York UniversityNCT06598397

Phase 1

Phase 1/2 Study: CD45RA Depleted Peripheral Stem Cell Addback to Prevent Viral and Fungal Infections Following Alternative Donor TCRab/CD19 Depleted Hematopoietic Stem Cell Transplant

The major morbidities of allogeneic hematopoietic stem cell transplant (HSCT) using donors that are not human leukocyte antigen (HLA) matched siblings are graf…

LeukemiaHigh Risk Acute Lymphoblastic LeukemiaHigh Risk Acute Myeloid Leukemia+11 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT06839456

Phase 3

Varenicline and Mobile Behavioral Assistance for Tobacco Cessation in HIV Care in India

The goal of this research study is to test an intervention to help quit tobacco use in participants with Human Immunodeficiency Virus (HIV). The study interve…

Human Immunodeficiency VirusSmoking CessationSmoking, Tobacco

Estimated

~$10 – $6,250

University of Colorado, DenverNCT05786547

Observational

Strategies to AchieVe Viral Suppression for Youth With HIV (The SAVVY Study)

Although there have been advances in antiretroviral treatment (ART) for HIV, adolescents and young adults living with HIV (AHIV) continue to have disparate HIV…

Human Immunodeficiency Virus (HIV) Infection

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT06886971

Phase 4

Prospective Observational Immunogenicity Trial of Gardasil-9 HPV Vaccine in People Living With Adequately Managed HIV

The primary objective of this study is to determine the magnitude and breadth of the serum antibody response to the nonavalent HPV vaccine (Gardasil-9) in adul…

Papillomavirus VaccinesHuman Immunodeficiency VirusPapillomavirus Infection+4 more

Estimated

~$10 – $6,250

Louisiana State University Health Sciences Center in New OrleansNCT05266898