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6 recruiting studies matching your filters

Oral Microbial and Immunological Characterization of Patients With Immune Dysfunction

Background: \- Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This condition can cause tooth loss if it is…

ImmunosuppressionPeriodontal DiseaseHealthy Subjects+1 more

Estimated

~$10 – $675

National Institute of Dental and Craniofacial Research (NIDCR)NCT01568697

Phase 2

Phase II Clinical Trial Evaluating the Safety Efficacy of Fc-Modified Anti-CD154 mAB (TNX-1500) in Kidney Transplant Recipients

The primary objective is to investigate the safety of TNX-1500, an FC-modified anti-CD154 mAb, in five kidney transplant recipients at 12 months.

Kidney TransplantKidney Transplant Failure and RejectionImmunosuppression+1 more

Estimated

~$10 – $7,500

Ayman Al Jurdi, MDNCT07204080

Pathological Myeloid Activation After Sepsis and Trauma Subtitle: Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis Pathobiology

The goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main quest…

Trauma InjurySepsisImmunosuppression+1 more

Estimated

~$10 – $750

University of FloridaNCT05616130

Phase 2

Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy

The purpose of this study is to determine the safety and efficacy of hand transplantation as a treatment for patients with loss of limb below the elbow, The st…

Immunosuppression

Estimated

~$10 – $7,500

Linda CendalesNCT02310867

Observational

Robotic Vascularized Composite Bladder Allograft Transplantation: A Phase 0 (First-in-Human), Single Institutional Study for Deceased-Donor Bladder Transplantation

This phase 0 trial tests the feasibility, functionality, and sustainability of vascularized composite bladder allograft transplantation in treating patients wi…

Neurogenic BladderBladder DysfunctionImmunosuppression

Estimated

~$10 – $6,250

University of Southern CaliforniaNCT05462561

Phase 1

A Phase I Feasibility Study of HSPC Infusion Following Total Lymphoid Irradiation and Anti-thymocyte Globulin in Patients With a Pre-existing, Well-functioning HLA-matched Living-donor Liver Transplant to Induce Immune Tolerance.

This clinical trial is being conducted to help liver transplant recipients safely discontinue toxic immunosuppressive drugs years after surgery. Lifelong use o…

Liver TransplantationImmune ToleranceImmune Tolerance/Drug Effects+6 more

Estimated

~$10 – $6,250

University of California, Los AngelesNCT07269041