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499 recruiting studies matching your filters

An Open-Label Prospective Randomized Trial of Family Donor-Derived ADV or CMV CTLs Plus Standard of Care (SOC) vs SOC Alone in Children, Adolescents and Young Adults Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) With Refractory ADV or CMV Infection/Viremia

Patients with refractory ADV or CMV infection post allogeneic stem cell transplant will be randomized to either Family donor-derived viral specific cytotoxic T…

CMVAdV InfectionAdV Reactivation+2 more

Estimated

~$10 – $6,250

New York Medical CollegeNCT07225972

Phase 3

PO Versus IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

This is a Phase III clinical randomized control trial to investigate differences between patient with an infected nonunion treated by PO vs. IV antibiotics. Th…

InfectionsInfected WoundNonunion of Fracture+6 more

Estimated

~$10 – $7,500

Major Extremity Trauma Research ConsortiumNCT05699174

Phase 4

Trial of Antibiotic Strategies for Kidney Transplant Recipients

The goal of this clinical trial is to learn if a common antibiotic called trimethoprim-sulfamethoxazole (TMP-SMX) can help prevent urinary tract infections (UT…

Kidney TransplantUrinary Tract Infection(UTI)Antibiotic Prophylaxis+2 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07106125

Phase 2

A Randomized, Double-Blind, Two-Part, Placebo-Controlled, Multicenter, Phase 2a Study to Evaluate Safety, Tolerability, and Efficacy of INNA-051 as Prophylaxis for Respiratory Tract Illness in Healthy Adults 18 to 45 Years of Age Who Are at Risk for Viral Respiratory Infections

Acute upper and lower respiratory infections are a major public health problem and a leading cause of morbidity and mortality worldwide. The purpose of this tr…

Viral Respiratory InfectionViral Respiratory Illnesses

Estimated

~$10 – $8,750

ENA Respiratory Pty LtdNCT07222670

Phase 2

A Phase IIb, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AZD5148 for Prevention of Recurrence of Clostridioides Difficile Infection in Individuals 18 Years of Age and Above

The purpose of this study is to evaluate the efficacy and safety of AZD5148 for prevention of recurrence of Clostridioides difficile infection in Individuals 1…

Clostridioides Difficile Infection

Estimated

~$10 – $7,500

AstraZenecaNCT07285213

Phase 2

A Phase 2 Randomized Double-blind Placebo-controlled Study To Evaluate The Efficacy And Safety Of Adjunctive Recombinant Human Plasma Gelsolin With Standard Care For Moderate-to-Severe ARDS Due To Pneumonia Or Other Infections

BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN pl…

Acute Respiratory Distress SyndromeInfections

Estimated

~$10 – $8,750

BioAegis Therapeutics Inc.NCT05947955

Observational

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through …

Substance Use DisordersHIV Infections

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT05816083

Phase 2

An Operationally Seamless Phase 2/3 Randomized, Open-label, Active-Controlled Study Evaluating the Safety and Efficacy of an Injectable Regimen of GS-3242 in Combination With Lenacapavir Versus Biktarvy (Bictegravir/Emtricitabine/Tenofovir Alafenamide) in Treatment-Naive People With HIV-1

The study will have two portions: Phase 2 and Phase 3. Phase 2 will further have 2 parts: Part A and Part B. The goal of Phase 2, Part A is to assess the effe…

HIV-1-infection

Estimated

~$10 – $7,500

Gilead SciencesNCT07708727

Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute Infections With, and Convalescence From, Emerging or Re-emerging Respiratory Viruses

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The global outbreak of COVID-19 is a majo…

COVID-19 Infection

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT04582903

Phase 1

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission: A Phase I/II Proof of Concept Study

The study will explore the effects of early intensive antiretroviral therapy (ART) with or without a broadly neutralizing antibody (bNAb) on achieving HIV remi…

HIV Infection

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT02140255

Phase 1

Phase 1 Study of the Safety of an Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection

Background: Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis, commonly known as mono. EBV infects more than 90% of the world s popula…

EBVEpstein-Barr Virus InfectionInfectious Mononucleosis+1 more

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT06908096

Phase 2

ImproviNg Coronary Vascular Health in Women With Risk Factors fOR Myocardial Infarction Type 2 (INFORM-2)

Women with HIV have an increased risk of having a myocardial infarction (heart attack) as compared to women without HIV. One of the mechanisms underlying the i…

HIV-1-infectionCoronary Microvascular DysfunctionMetabolic Disease

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06843902