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Pathophysiological Evaluation of Idiopathic Intracranial Hypertension Using Glymphatic and Connectomic Imaging
Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure leading to symptoms like papilledema, headache, and cognitive dys…
Idiopathic Intracranial Hypertension (IIH)Glymphatic System
Estimated
~$10 – $750
Thomas Jefferson UniversityNCT06950099
Observational
External Lumbar Drainage to Abort Severe Traumatic IntraCranial Hypertension: A Phase 1 Randomized, Allocation-concealed, Open-label, Safety and Feasibility Clinical Trial
The goal of this phase 1 randomized controlled safety and feasibility clinical trial are to determine the safety of external lumbar drainage (ELD) in select pa…
Severe Traumatic Brain InjuryIntracranial Hypertension
Estimated
~$10 – $6,250
Brain Trauma FoundationNCT05889650
Phase 4
A Phase IV Placebo-controlled Single Center Trial for Tirzepatide in Idiopathic Intracranial Hypertension Trial (TIIHT)
This will be a randomized, double-blind, parallel, placebo-controlled trial of 60 participants. The primary analysis will be a statistical comparison of the es…
Idiopathic Intracranial Hypertension (IIH)
Estimated
~$10 – $6,250
Duke UniversityNCT07191873