This will be a randomized, double-blind, parallel, placebo-controlled trial of 60 participants. The primary analysis will be a statistical comparison of the es…

Idiopathic Intracranial Hypertension (IIH)

~Estimated

~$10 – $6,250

Duke UniversityNCT07191873

Pathophysiological Evaluation of Idiopathic Intracranial Hypertension Using Glymphatic and Connectomic Imaging

Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure leading to symptoms like papilledema, headache, and cognitive dys…

Idiopathic Intracranial Hypertension (IIH)Glymphatic System

~Estimated

~$10 – $750

Thomas Jefferson UniversityNCT06950099

Observational

External Lumbar Drainage to Abort Severe Traumatic IntraCranial Hypertension: A Phase 1 Randomized, Allocation-concealed, Open-label, Safety and Feasibility Clinical Trial

The goal of this phase 1 randomized controlled safety and feasibility clinical trial are to determine the safety of external lumbar drainage (ELD) in select pa…

Severe Traumatic Brain InjuryIntracranial Hypertension

~Estimated

~$10 – $6,250

Brain Trauma FoundationNCT05889650