Kidney failure has been recognized as one of the most costly chronic conditions among United States Veterans. Approximately 13,000 Veterans develop kidney fail…

End Stage Renal DiseaseHypertensionExtracellular Volume Overload+1 more

~Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT04163614

Observational

Randomized, Controlled, Double-blind Trial of Lower Versus Higher Dialysate Bicarbonate in Hospitalized Maintenance Hemodialysis Patients

QTc prolongation and premature ventricular contractions (PVCs) are common in hemodialysis (HD) patients and are associated with sudden cardiac death. It is kn…

Peri-dialytic Cardiac RhythmsIntradialytic HypotensionElectrolyte Changes+2 more

~Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT05814146

Phase 3

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor A Randomized, Double-blind, Placebo-controlled, Cross Over Explorative Study

Currently, there is no medication available to adequately treat patients undergoing hemodialysis who are suffering from intradialytic hypotension (IDH). Medica…

Intradialytic Hypotension

~Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT05834777