The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and…

Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery

~Estimated

~$10 – $6,250

Ochsner Health SystemNCT07023185

Phase 2

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty - a Randomized, Two by Two Factorial, Double-blind, Placebo-controlled Clinical Trial

The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflamm…

Knee Replacement SurgeryOsteoarthritis, Knee

~Estimated

~$10 – $7,500

Chad BrummettNCT06234631

Phase 3

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established pe…

Total Knee Replacement SurgeryPost-operative Pain

~Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07548385