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Observational
Clinical Onboard Utilization of Image Guided Radiation Therapy With Magnetic Resonance (CONFIRM): A Master Protocol
This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to…
Gastric CancerInvasive Breast Cancerin Situ Breast Cancer+3 more
Brigham and Women's HospitalNCT04368702
Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often …
HNSCCOral Cavity CancerOropharynx Cancer+2 more
University Hospital FreiburgNCT05337631
Observational
A Stepped Wedge Cluster Randomized Trial Comparing a Navigation-Based Multilevel Intervention With Treatment as Usual to Improve Initiation of Timely Postoperative Radiation Therapy in Adults With Head and Neck Cancer
The goal of this clinical trial is to compare the effectiveness of a navigation-based multilevel intervention (ENDURE) with treatment as usual (TAU) to improve…
Head and Neck CancerHead and Neck Squamous Cell CarcinomaOropharynx Cancer+2 more
Medical University of South CarolinaNCT05793151
Phase 2
A Phase II Study of Sacituzumab Govitecan in Combination With Cetuximab in Patients With Recurrent Metastatic HNSCC That Has Progressed After First-Line Therapy
The purpose of this study to find out whether sacituzumab govitecan in combination with cetuximab is an effective and safe treatment approach for people with r…
Squamous Cell Carcinoma of Head and NeckSinus CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer CenterNCT07063212