Browse Studies — Arctuva

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of Lepodisiran to Investigate the Effect on Coronary Plaque in Adults With Elevated Lp(a) Who Have Established Atherosclerotic Cardiovascular Disease or Are at Risk for a First Cardiovascular Event

Lipoprotein(a), also known as Lp(a), is a protein that carries cholesterol and proteins in your blood. People with high Lp(a) have a higher risk for heart dise…

AtherosclerosisCardiovascular DiseasesLipoprotein(a)

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07613294

Phase 2

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-7262 as Monotherapy and When Coadministered With Enlicitide Decanoate in Adults With Elevated Lipoprotein(a)

Researchers designed a trial medicine called MK-7262 to lower levels of Lp(a) in the blood. Researchers want to learn about giving MK-7262 with another trial m…

Lipoprotein(a)

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07614984

Phase 3

A Single Arm, Multicenter, Open-label Extension (OLE) Trial to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) in Participants Who Completed the Parent Lp(a)HORIZON Trial

This open-label extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed the double-blind parent s…

Cardiovascular Disease and Lipoprotein(a)

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT07517263