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29 recruiting studies matching your filters

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study

Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal …

Liver Transplant SurgeryColorectal Cancer MetastaticColon Cancer Liver Metastases

Estimated

~$10 – $750

Northwestern UniversityNCT06698146

Viability Assessment Using Flavin Mononucleotide (FMN) Measured in Perfusate and Bile During Normothermic Machine Perfusion: an International, Multi-center Validation Study

Discarded perfusate samples will be collected from donors after circulatory death (DCD) or donors after brain death (DBD) organs during the machine perfusion p…

Liver Transplant Disorder

Estimated

~$10 – $750

The Cleveland ClinicNCT07315204

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

This study is being done to test blood, urine and tissue samples to see if this can help decide if CKD (Chronic Kidney Disease), AR (Acute Rejection) and HCV (…

Liver TransplantHepatitis CChronic Kidney Disease+1 more

Estimated

~$10 – $750

Northwestern UniversityNCT01644903

Phase 1

A Phase I Study of Autologous Adipose-derived Mesenchymal Stromal Cells in Preventing Biliary Complications After Living Donor Liver Transplant

The purpose of this study is to assess the safety of autologous Adipose-Derived Mesenchymal Stem Cell for use in End-Stage Liver Disease patients undergoing th…

Liver Transplant; ComplicationsLiver Diseases

Estimated

~$10 – $6,250

Mayo ClinicNCT06649864

US National OCS Liver Perfusion (OLP) Registry

This Registry is a sponsor-initiated, multi-center, observational, post-approval registry with an independent academic oversight. TransMedics has contracted w…

Liver Transplant

Estimated

~$10 – $1,125

TransMedicsNCT05940857

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure (ACLF): iNdications and outComEs

Management of ACLF is mainly supportive. The poor outcomes lead physicians to consider liver transplantation as an option, even if controversial. In sicker rec…

Liver DiseasesLiver CirrhosisAcute-On-Chronic Liver Failure+1 more

Estimated

~$10 – $750

European Foundation for Study of Chronic Liver FailureNCT04613921

Observational

Normothermic Machine Perfusion of Steatotic Livers for Expansion of Donor Organ Pool

The goal of this clinical trial is to assess the ability of Normothermic Machine Perfusion (NMP) to resuscitate moderately steatotic livers for transplantation…

Liver Transplant

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06088758

Observational

HEalth Advocate for Liver Transplant - Pilot

The Health Advocate for Liver Transplant (HEAL-Tx) Pilot is a nonrandomized, open-label intervention pilot of a health advocate intervention aimed to assess fe…

Liver Transplant; ComplicationsPediatric ALL

Estimated

~$10 – $5,625

University of California, San FranciscoNCT05700799

Phase 1

A 12-Month, Open-Label Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Siplizumab as Induction Therapy in Patients With Autoimmune Liver Diseases Undergoing Liver Transplantation (SET-SAIL)

There is a significant unmet need for safe and effective therapeutic approaches to prevent immune-mediated graft injury and its complications in liver transpla…

Autoimmune Liver DiseaseLiver Transplant DisorderAutoimmune Hepatitis+3 more

Estimated

~$10 – $7,500

Elizabeth C. VernaNCT06455280

Phase 4

Exploratory Use of CMV Immunoglobulin in High Risk (D+R-) Transplant Recipients at the End of Antiviral Prophylaxis to Decrease the Risk of Late CMV Infection

This study is being done to find out if administering CytoGam® after the end of standardly prescribed preventive antiviral treatment can help transplant recipi…

CytomegalovirusOrgan TransplantKidney Transplant; Complications+2 more

Estimated

~$10 – $7,500

Camille N. Kotton, MDNCT06958796

Post-discharge Glycemic Control After Liver Transplant and Impact on Transplant Outcomes

This investigator initiated study aims to describe continuous glucose monitoring (CGM) based glycemic metrics after discharge from liver transplant and assess …

Liver TransplantPost Transplant DiabetesType 2 Diabetes

Estimated

~$10 – $750

Icahn School of Medicine at Mount SinaiNCT07216508

Phase 4

Hypothermic Oxygenated Perfusion (HOPE) Against Cancer Recurrence in HCC Liver Transplantation - International Multicentre Parallel Group Interventional RCT

Liver transplantation is often performed to treat liver cancer, or hepatocellular carcinoma (HCC), in patients with impaired liver function due to cirrhosis. A…

Liver TransplantationHCCOncological Outcomes

Estimated

~$10 – $7,500

Philipp DutkowskiNCT06717919