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6 recruiting studies matching your filters

A Phase 3 Randomized, Double-Blind, Active-Controlled Study of Palazestrant With Ribociclib Versus Letrozole With Ribociclib for the First-Line Treatment of ER+, HER2- Advanced Breast Cancer (OPERA-02)

This phase 3 clinical trial compares the efficacy and safety of palazestrant with ribociclib to letrozole and ribociclib in women and men who have not received…

Breast CancerLocally Advanced Breast CancerMetastatic Breast Cancer+2 more

Estimated

~$10 – $8,750

Olema Pharmaceuticals, Inc.NCT07085767

Phase 1

A Phase I/II, Multi-site, Open-label, Two-part Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of BNT323 in Combination With BNT327 in Participants With Advanced Breast Cancer

This is a Phase I/II, multi-site, open-label, two-part study designed to evaluate the efficacy, safety, optimized dose and contribution of components of BNT323…

Locally Advanced Breast CancerUnresectable Breast CarcinomaMetastatic Breast Cancer

Estimated

~$10 – $7,500

BioNTech SENCT06827236

Phase 1

Does Ablation (Cryoablation or Histotripsy) Boost Immune Response Improving the Benefits of Pembrolizumab in Patients With Metastatic or Locally Advanced Triple Negative Breast Cancer?

Participants will have a confirmed diagnosis of metastatic breast cancer and will receive pembrolizumab in combination with ablation (cryoablation or histotrip…

Metastatic Breast CancerBreast CancerBreast Cancer Stage IV+5 more

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT06246968

Phase 2

I-SPY Trial (Investigation of Serial Studies to Predict Your Therapeutic Response With Imaging And moLecular Analysis 2)

The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which t…

Breast NeoplasmsBreast CancerBreast Tumors+8 more

Estimated

~$10 – $7,500

QuantumLeap Healthcare CollaborativeNCT01042379

Phase 2

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

This randomized, placebo-controlled trial aims to assess the feasibility, acceptability, and preliminary efficacy of memantine and the University of Carolina (…

Breast CancerLocally Advanced Breast CancerCognitive Impairment+5 more

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT06727773

Phase 1

Contrast Enhanced Digital Mammography for Predicting Pathologic Complete Response After Neoadjuvant Chemotherapy

The purpose of this study is to compare a special type of mammogram that uses a contrast agent called contrast-enhanced digital mammography with contrast-enhan…

Breast CancerLocally Advanced Breast CancerNeoadjuvant Chemotherapy+3 more

Estimated

~$10 – $7,500

Alison StopeckNCT06220214