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14 recruiting studies matching your filters
Phase 1
A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG462 as a Single Agent and in Combination in Patients With MTAP-deleted Advanced or Metastatic Solid Tumors
This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an open-labe…
Locally Advanced Solid Tumor
Estimated
~$10 – $8,750
Tango Therapeutics, Inc.NCT05732831
Phase 1
A Phase 1a/1b Study of the Selective Tyrosine Kinase Inhibitor NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
Phase 1a/1b dose escalation and expansion study designed to evaluate the safety and tolerability of NVL-330, determine the recommended Phase 2 dose (RP2D), and…
Locally Advanced Solid TumorMetastatic Solid Tumor
Estimated
~$10 – $8,750
Nuvalent Inc.NCT06521554