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91 recruiting studies matching your filters

A Long-term Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder for Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease

The primary objective of this study is to evaluate the safety and tolerability of the long-term use of TPIP in participants with PH-ILD from Study INS1009-311 …

Pulmonary HypertensionInterstitial Lung Disease

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Insmed IncorporatedNCT07234032

Observational

Ventilator Pressure and Optimization of Compliance and Hemodynamics: VPOCH Trial

In preterm infants \< 34 weeks' gestation at birth receiving respiratory support with invasive positive pressure ventilation, the positive end-expiratory press…

Bronchopulmonary DysplasiaPulmonary Hypertension Due to Lung Diseases and HypoxiaExtreme Prematurity+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Alabama at BirminghamNCT06512935

Phase 2

An Open-Label Study to Assess the Hemodynamic Effect and the Safety of TX000045 After 16 Weeks of Treatment in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

The primary purpose of this study is to assess the effect of TX000045 on pulmonary vascular resistance (PVR) in participants with pulmonary hypertension second…

Hypertension, PulmonaryLung Diseases, Interstitial

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Tectonic Operating Company, Inc.NCT07473700

Phase 3

Evaluation of Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74 PET/CT Imaging)

Background: Injury or diseases of the heart and lung can sometimes cause scar tissue (fibrosis) to build up in those organs. Current imaging scans can see thi…

Allogeneic Stem Cell TransplantationLung Allograft TransplantationInterstitial Lung Disease+3 more

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT07613099

Phase 3

A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel Group Study to Evaluate the Efficacy and Safety of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease

The primary objective of this study is to evaluate the effect of 24-weeks of once daily treatment with TPIP versus placebo on exercise capacity in adults with …

Pulmonary HypertensionInterstitial Lung Disease

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Insmed IncorporatedNCT07179380

Phase 3

A Study to Evaluate the Dose-exposure, Safety, and Exploratory Efficacy of Nerandomilast in Children and Adolescents From 2 Years to Less Than 18 Years of Age With Fibrosing Interstitial Lung Disease (Part A: Double-blind, Placebo-controlled in Children From 6 to Less Than 18 Years of Age and Open-label Active Treatment in Children From 2 to Less Than 6 Years of Age), Followed by an Open-label Phase With Active Treatment (Part B)

This study is open to children and adolescents aged 2 to 17 years with interstitial lung disease (ILD). Nerandomilast has just been approved in some countries …

Fibrosing Interstitial Lung Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Boehringer IngelheimNCT07366034

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

The purpose of this study is to obtain biologic materials from the blood, airways and/or urine of normal individuals and individuals with lung disease. The nor…

Chronic Obstructive Pulmonary Disease (COPD)SmokingSmoking Cessation+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Weill Medical College of Cornell UniversityNCT01776398

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Background: People with sickle cell disease (SCD) have problems with their heart, brain, kidneys, liver, and lungs as they age. These problems may improve aft…

Mortality in Sickle CellSickle Cell Cardiopulmonary ComplicationsSickle Cell Organ Damage+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT05213572

Phase 4

Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease

The MAC-HS study is a testing whether hypertonic saline helps improve symptoms and clearance of mycobacteria in patients with M. avium complex lung infections.

Nontuberculous Mycobacterial Lung DiseaseNontuberculous Mycobacterium Infection

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Oregon Health and Science UniversityNCT04921943

Phase 3

An Open-label Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease (TETON-OLE)

Study RIN-PF-302 is designed to evaluate the long-term safety and tolerability of inhaled treprostinil in subjects with idiopathic pulmonary fibrosis or progre…

Idiopathic Pulmonary FibrosisInterstitial Lung DiseaseProgressive Pulmonary Fibrosis

Estimated

~$50 – $2,100

Actual pay is set by the research site.

United TherapeuticsNCT04905693

Phase 2

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

There is no standard of care therapy for patients with granulomatous-lymphocytic interstitial lung disease (GLILD) seen in common variable immunodeficiency (CV…

Interstitial Lung DiseaseCommon Variable Immunodeficiency

Estimated

~$75 – $1,800

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT04925375

Phase 1

A Phase I Single Center Study Evaluating 68GA-FAPI-46 PET/CT in Patients With Interstitial Lung Disease

The purpose of this research is to better understand the distribution of an investigational radioactive imaging agent called 68Ga-FAPI-46 in the lungs of peopl…

Interstitial Lung Disease

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Mayo ClinicNCT07817563