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75 recruiting studies matching your filters

A Randomized, Double-blind, Placebo-controlled Study of Quinacrine (QC) in Participants With Active Cutaneous Lupus Erythematosus (CLE), Including Subacute CLE (SCLE) and/or Discoid LE (DLE), With or Without Concurrent Systemic Manifestations

The research study is being conducted to learn more about how patients with cutaneous lupus erythematosus (CLE) respond to the use of quinacrine. Quinacrine is…

Cutaneous Lupus Erythematosus (CLE)

Estimated

~$10 – $7,500

Victoria WerthNCT07694336

Observational

Transforming Health Habits: Evaluating an Online Wellness Program for Individuals With Rheumatological Conditions and Mood Disorders

The goal of this project is to critically evaluate the effectiveness of an online health program designed to improve diet and self-care in patients with rheuma…

Rheumatoid ArthritisSjogren's SyndromeSystemic Lupus Erythematosus+6 more

Estimated

~$10 – $7,500

Terry L. WahlsNCT07180537

Phase 1

A Phase1b, Multiple Ascending Dose, Open-label, Non-randomized Study Evaluating the Pharmacokinetics, Safety, and Efficacy of ABBV-319 in Subjects With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by B cell hyperactivity. Sjorgren's disease (SjD) is a chronic, mult…

Dry Eye SyndromeSystemic Lupus Erythematosus

Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus

Study Description: Systemic lupus erythematosus (SLE) occurs predominantly in women and is driven by type I interferon dysregulation and neutrophil hyperrespo…

Systemic Lupus Erythematosus (Sle)

Estimated

~$10 – $5,625

National Heart, Lung, and Blood Institute (NHLBI)NCT06032923

Phase 3

A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Trial to Assess the Efficacy, Safety and Tolerability of Cenerimod in Adult Patients With Systemic Lupus Erythematosus and Active Lupus Nephritis in Combination With Background Therapy

The goal of this clinical trial is to learn if cenerimod, on top of regular treatment, works to treat active lupus nephritis in adults with systemic lupus eryt…

Nephritis, LupusLupus Erythematosus, Systemic

Estimated

~$10 – $8,750

Viatris Innovation GmbHNCT07201129

Systemic Lupus Erythematosus in Gullah Health

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies, multiple organ involvement, and diverse clinical…

Systemic Lupus Erythematosus

Estimated

~$10 – $750

Medical University of South CarolinaNCT00756769

Phase 2

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

The goal of this clinical trial is to learn if VENT-03 works to treat patients with cutaneous lupus erythematosus (CLE) who may or may not have systemic lupus …

Cutaneous Lupus Erythematosus (CLE)Systemic Lupus ErythematosusSLE+2 more

Estimated

~$10 – $8,750

Ventus Therapeutics U.S., Inc.NCT07260877

Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions

The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This w…

Juvenile Idiopathic ArthritisSystemic Lupus ErythematosusFibromyalgia

Estimated

~$10 – $675

Children's National Research InstituteNCT04833465

Phase 1

A Phase I, Multicenter, Open-label Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Patients With Severe, Treatment-refractory Systemic Lupus Erythematosus

The purpose of this study is to evaluate the safety and tolerability of P-CD19CD20-ALLO1 in participants with highly active, severe, refractory SLE with or wit…

Systemic Lupus Erythematosus

Estimated

~$10 – $8,750

Genentech, Inc.NCT06984341

Phase 1

A Phase 1, First-time-in-human, Four-part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GSK4527363 in Healthy Participants (Part A), Participants With Active Systemic Lupus Erythematosus (Part B), Healthy Participants of Chinese and Japanese Descent (Part C) and Participants With Interstitial Lung Disease Associated With Connective Tissue Disease (Part D)

This study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of GSK4527363 in healthy participants (Part A), particip…

Systemic Lupus Erythematosus

Estimated

~$10 – $7,500

GlaxoSmithKlineNCT06576271

Phase 4

Pilot Trial of Belimumab in Early Lupus

This two year study will evaluate the effects of giving belimumab (Benlysta) to patients with Early Lupus. Early lupus is a diagnosis of lupus within 2 years. …

Lupus Erythematosus, SystemicLupus Erythematosus

Estimated

~$10 – $7,500

Northwell HealthNCT03543839

Testing of an Educational Tool for Patients With Melanoma and Concomitant Autoimmune Disease Who Are Candidates for Adjuvant Therapy With Immune Checkpoint Inhibitors: Acceptability and Usability With Patients and Providers

This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who recei…

Ankylosing SpondylitisAutoimmune DiseaseCrohn Disease+10 more

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT04751396