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Phase 1
An Open-Label, Single-Arm, Phase 1/2 Dose-Escalation Trial of Long-Acting Recombinant Human IL-7 (NT-I7, Efineptakin-Alpha) for Idiopathic CD4 Lymphopenia
Background: Idiopathic CD4 lymphopenia (ICL) is a syndrome characterized by low levels of certain immune cells called CD4 T cells. The low CD4 T cells renders…
Idiopathic CD4 Lymphopenia
National Institute of Allergy and Infectious Diseases (NIAID)NCT05600920
Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation
To learn how radiation treatment may affect your responses to vaccines against pneumonia.
Pneumococcal VaccineEsophageal CancerLymphopenia+1 more
M.D. Anderson Cancer CenterNCT06181656
Phase 1
A Phase 1 Evaluation of the Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)
Background: People with Idiopathic CD4 lymphopenia (ICL) have lower numbers of a type of white blood cell called CD4 cells. White blood cells fight against in…
Idiopathic CD4 Lymphopenia
National Institute of Allergy and Infectious Diseases (NIAID)NCT04097561