Browse Studies — Arctuva

Phase 2

Randomized Phase 2 Trial of Ruxolitinib in Combination With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma.

The purpose of this research is to test the safety and effectiveness of the investigational drug ruxolitinib when it is combined with standard of care treatmen…

GlioblastomaBrain CancerGlioblastoma Multiforme+4 more

Estimated

~$10 – $7,500

Baptist Health South FloridaNCT06991101

Phase 1

A Phase 1 and Randomized Phase 2 Trial of Selinexor and Temozolomide in Recurrent Glioblastoma

This phase I/II trial tests the safety, side effects and best dose of selinexor given in combination with the usual chemotherapy (temozolomide) and compares th…

Recurrent Glioblastoma, IDH-WildtypeRecurrent MGMT-Methylated Glioblastoma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05432804

Phase 2

A Phase 2 Randomized Open-Label Pilot Study of Granulocyte Colony Stimulating Factor (G-CSF) to Preserve Brain Structure and Function Following Standard Chemoradiation in Patients With Newly Diagnosed MGMT-Methylated Glioblastoma

This research study involves the study of granulocyte colony stimulating factor (G-CSF) in patients with MGMT-methylated glioblastoma multiforme (GBM) that are…

MGMT-Methylated GlioblastomaGlioblastoma (GBM)Newly Diagnosed Glioblastoma Multiforme

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06649851

Phase 1

A Phase I/IIa Study to Evaluate the Efficacy of DB107-RRV (Formerly Toca511), Administered to Subjects at Time of Resection and Intravenously Thereafter, in Combination With DB107-FC (Formerly Toca FC) and Radiation Therapy or DB107-FC, Temozolomide (TMZ) and Radiation Therapy in Patients With Newly Diagnosed High Grade Glioma

This is a multicenter, open-label study of DB107-RRV (formerly Toca 511) and DB107-FC (formerly Toca FC) when administered following surgical resection in newl…

High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06504381