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19 recruiting studies matching your filters

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Phase 2

Phase 2 Study Of Imetelstat for Patient With Myelodysplastic/Myeloproliferative Neoplasms

To learn if imetelstat can help to control MDS/MPNs.

Phase IIImetelstatMyelodysplastic (MDS) / Myeloproliferative (MPN) Diseases

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT07549451

The MPN PROGRESSion Registry: A Retrospective and Prospective Observational Study Collecting Patient-Reported Outcomes, Electronic Health Records, and Claims Data to Track Symptoms, Treatments, and Disease Progression in Individuals Diagnosed With Myeloproliferative Neoplasms (MPNs).

The MPN PROGRESSion Registry is a multi-year, observational research study designed to improve understanding of myeloproliferative neoplasms (MPNs)-a group of …

Polycythemia VeraET (Essential Thrombocythemia)Polycythemia Vera (PV)+52 more

Phase 1

An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).

Myeloproliferative NeoplasmMPNEssential Thrombocythemia+2 more

Estimated

~$10 – $6,250

University of California, IrvineNCT05123365

Phase 2

A Multi-Center Phase II Study of Selinexor in Treating Recurrent or Refractory Wilms Tumor and Other Pediatric Solid Tumors

The purpose of this study is to find out whether selinexor is an effective treatment for people who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPN…

Wilms TumorRhabdoid TumorMalignant Peripheral Nerve Sheath Tumors+4 more

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05985161

Phase 2

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

The purpose of this clinical trial is to compare drug combinations to learn which drugs work best to prevent graft-versus-host-disease (GVHD) in people who hav…

AML (Acute Myelogenous Leukemia)Acute Lymphoid Leukemia (ALL)Acute Leukemia (Category)+8 more

Estimated

~$10 – $7,500

Center for International Blood and Marrow Transplant ResearchNCT06859424

Phase 2

A Phase II Study of ASTX727 in Patients With PRC2 Loss Malignant Peripheral Nerve Sheath Tumor (MPNST)

The purpose of this study is to see whether the study drug ASTX727 is an effective treatment for people who have MPNST with a PCR2 mutation. ASTX727 is a comb…

Malignant Peripheral Nerve Sheath Tumors (MPNST)

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT04872543

Phase 1

The ABNL-MARRO 001 Study: A Phase 1/2 Study of Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes.

ABNL-MARRO (A Basket study of Novel therapy for untreated MDS/MPN and Relapsed/Refractory Overlap Syndromes) is an international European-American cooperation …

MDS/MPN

Estimated

~$10 – $7,500

Michael SavonaNCT04061421