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639 recruiting studies matching your filters

A Phase1 b/2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of GSK5764227 Alone and in Combination in Participants With Previously Treated Advanced Unresectable or Metastatic Gastrointestinal Solid Tumors

This study will check how well a new medicine, Risvutatug rezetecan, (Ris-Rez, also known as GSK5764227) works, how safe it is and how the body handles it in p…

Gastrointestinal Neoplasms

Estimated

~$10 – $7,500

GlaxoSmithKlineNCT06885034

Phase 2

An Open-label Phase 2a Study to Evaluate the Safety and Efficacy of AlloNK®, an Allogeneic Cord Blood-derived NK Cell Therapy, in Combination With Rituximab in Relapsing Forms of B-cell Dependent Rheumatologic Diseases

A Basket Trial of Refractory Rheumatoid Arthritis (RA), Sjögren's Disease (SjD), Idiopathic Inflammatory Myopathies (IIMs) and Systemic Sclerosis (SSc) subject…

Refractory Rheumatoid Arthritis (RA)Idiopathic Inflammatory Myopathies (IIMs)Systemic Sclerosis (SSc)+6 more

Estimated

~$10 – $8,750

Artiva Biotherapeutics, Inc.NCT06991114

Observational

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

Digital mental health interventions are a cost-effective and efficient approach to expanding the accessibility and impact of psychological treatments; however,…

Anxiety Disorders and SymptomsDepressive Symptoms

Estimated

~$10 – $6,250

Boston University Charles River CampusNCT05567640

Phase 1

A Phase 1/2 Dose Escalation Study of CRN09682 With an Expansion Phase in Participants With Progressive Metastatic Somatostatin Receptor Type 2 (SST2)-Expressing Neuroendocrine Neoplasms (NENs) and Other SST2-Expressing Solid Tumors

This Phase 1/2, multicenter, open-label, FIH study aims to evaluate the safety, tolerability, PK, and preliminary antitumor activity of CRN09682 in participant…

SST2-positive Neuroendocrine NeoplasmsNeuroendocrine TumorsNeuroendocrine Neoplasm

Estimated

~$10 – $8,750

Crinetics Pharmaceuticals Inc.NCT07129252

Observational

Self-Compassion, Health, and Empowerment: A Randomized Controlled Trial for Chinese Immigrant Women Experiencing Intimate Partner Violence

Intimate partner violence (IPV) can have serious and lasting effects on women's mental health and well-being. Chinese immigrant women in the United States ofte…

Intimate Partner Violence (IPV)Depression and/or Anxiety SymptomsPTSD - Post Traumatic Stress Disorder

RecoverPC: A Phase 2 Study of RElugolix Versus GnRH Agonist Quality of Life (QOL) and Testosterone reCOVERy in Men With Prostate Cancer

This study is testing the way that approved androgen deprivation therapy treatments, Leuprolide and Relugolix, for prostate cancer affect quality of life, bloo…

Prostate CancerProstatic Neoplasms

Estimated

~$10 – $7,500

Dana-Farber Cancer InstituteNCT05765500

Observational

Exploration of Novel Imaging Biomarkers on OCT for Ublituximab Treatment Response in Multiple Sclerosis

The purpose of the research study is to explore new retinal imaging biomarkers of immune cell activity in MS during use of ublituximab (Briumvi) treatment. A b…

Multiple Sclerosis (MS) - Relapsing-remitting

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT06864936

Remote Monitoring in Progressive Supranuclear Palsy, an Alzheimer's Disease Related Dementia

This is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speec…

Progressive Supranuclear PalsyParkinson DiseaseMSA - Multiple System Atrophy

Estimated

~$10 – $750

Massachusetts General HospitalNCT04753320

Phase 3

A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of Remibrutinib in Patients With Secondary Progressive Multiple Sclerosis

The purpose of this study is to provide efficacy and safety data for remibrutinib in patients with secondary progressive multiple sclerosis (SPMS)

Secondary Progressive Multiple Sclerosis (SPMS)

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT07225504

Phase 4

Vaginal Estradiol Versus Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms, Dysbiosis and Markers of Latency Reversal in Menopausal Women Living With HIV

This is a research study about the effects of vaginal estradiol compared to moisturizer on vaginal symptoms of menopause and the microbiome in women with HIV. …

Menopausal ComplaintsVaginal AtrophyGenitourinary Symptoms+4 more

Estimated

~$10 – $6,250

Albert Einstein College of MedicineNCT07526948

Phase 3

A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Monotherapy Study to Evaluate Efficacy of Roluperidone on Negative Symptoms in Adult Subjects With Schizophrenia, Followed by a 52-Week, Randomized, Double-Dummy Phase to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications

Evaluate the efficacy, as well as safety and pharmacokinetics, of Roluperidone in improving the negative symptoms of schizophrenia in adult subjects in Phase A…

Negative Symptoms of Schizophrenia

Estimated

~$10 – $7,500

Minerva NeurosciencesNCT07565428

Phase 2

Assessing Follow-Up Effects Post-Discontinuation of Hyperbaric Oxygen Therapy on Cognitive Function, Mental Health, and Quality of Life in Veterans

This study is designed to better understand the long-term effects of hyperbaric oxygen therapy (HBOT). Our goal is to determine whether improvements after trea…

Traumatic Brain InjuryPost-Concussive SymptomsPost-Traumatic Stress Disorder

Estimated

~$10 – $7,500

Summit Hyperbarics and WellnessNCT07732374