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Phase 1
Targeting Myeloid-Derived Suppressor Cells in Patients With Recurrent/Progressive Grade 4 Glioma: Phase 1 Trial of Sitagliptin
Sitagliptin, when combined with standard-of-care drug bevacizumab, is being tested to 1) find out if it is effective at treating gliomas that have returned or …
GliomaGlioblastomaRecurrent Glioma+2 more
Kailin Yang, MD, PhDNCT07541781
Phase 1
Phase I Study of Replication-Competent Adenovirus-Mediated Double Suicide Gene Therapy With Stereotactic Radiosurgery in Patients With Recurrent or Progressive High Grade Astrocytomas
The primary goal of this Phase I study is to determine the maximum tolerated dose of oncolytic adenovirus mediated double suicide-gene therapy in combination w…
Malignant Glioma of BrainAstrocytomaMalignant Astrocytoma+6 more
Henry Ford Health SystemNCT05686798