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28 recruiting studies matching your filters
Registry Study of Children and Adults Patients With Relapsed, Refractory, or Progressive Sonic Hedgehog Medulloblastoma Harboring U1 Mutation
The purpose of this study is to create a biobank for patients diagnosed with Sonic Hedgehog Medulloblastoma at Baylor College of Medicine/Texas Children's Canc…
Medulloblastoma RecurrentMedulloblastoma, Childhood, RecurrentMedulloblastoma, SHH-activated and TP53 Mutant+1 more
Estimated
~$10 – $1,125
Mohammad H. Abu ArjaNCT07242963
Phase 1
Atovaquone Combined With Radiation in Children With Malignant Brain Tumors
The goal of this interventional study is to Assess the safety and tolerability of atovaquone in combination with standard radiation therapy (RT) for the treatm…
High-grade GliomaMedulloblastomaDiffuse Intrinsic Pontine Glioma+1 more
Estimated
~$10 – $6,250
Emory UniversityNCT06624371
Phase 1
Repurposing Ibrutinib for Chemo-Immunotherapy in a Phase 1b Study of Ibrutinib With Indoximod Plus Metronomic Cyclophosphamide and Etoposide for Pediatric Patients With Brain Cancer
Recent lab-based discoveries suggest that IDO (indoleamine 2,3-dioxygenase) and BTK (Bruton's tyrosine Kinase) form a closely linked metabolic checkpoint in tu…
EpendymomaMedulloblastomaGlioblastoma+1 more
Estimated
~$10 – $7,500
Theodore S. JohnsonNCT05106296
Phase 2
SJiMB21: Phase 2 Study of Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
This is a multi-center, multinational phase 2 trial that aims to explore the use of molecular and clinical risk-directed therapy in treatment of children 0-4.9…
Medulloblastoma
Estimated
~$10 – $6,250
St. Jude Children's Research HospitalNCT05535166